1. Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-related Diseases via Anti-oxidation and AMPK Activation
Xu Zhifang 1, 2 ;Feng Wei 3 ;Shen Qian 4 ;Yu Nannan 1 ;Yu Kun 1 ;Wang Shenjun 1, 2 ;Chen Zhigang 4 ;Seiji Shioda 5 ;Guo Yi 1, 2 ;
1 Acu-moxibustion and Tuina Department, Tianjin University of Traditional Chinese Medicine, Tianjin , China ; 2 Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin , China ; 3 South Branch of Guang#cod#x02019;anmen Hospital, China Academy of Chinese Medical Science, Beijing , China ; 4 Dongfang hospital, Beijing University of Chinese Medicine, Beijing , China ; 5 Peptide Drug Innovation, Global Research Center for Innovative Life Science, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo , Japan ;
Figure 2. The structures of berberine and other key protoberberine-type alkaloids contained in RC .
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