1. Comparison of the study findings: Male & female
HEALTH-RELATED QUALITY OF LIFE AND NUTRITIONAL STATUS OF PATIENTS WITH HIV INFECTION _ A DUBLIN HIV COHORT STUDY
S George¹, S Keating², F Lyons², F Mulcahy², G Courtney², S Clarke², C Bergin², M Gibney³, M Codd¹
¹ School of Public Health, Physiotherapy and Population Studies, University College, Dublin,
² GUIDE Clinic, St. James Hospital, Dublin, ³ Institute of Food and Nutrition, University College, Dublin
RESULTS
Participants: Total n = 102
Male = 80 (78.4 %)
Female = 22 (21.6 %)
Age : Mean (+ sd) = 41 ( + 8.8) years
Ethnicity : Caucasians : 85 %
African Black : 13 %
Other : 2 %
BMI : Mean (+ sd) = 25.4 (+ 4.3) Kg/m²
Treatment Status : 95 % on ART
HRQOL Results
Health-related Quality of life Mean Summary Scores :
Physical Health = 52.5 (+ 8.8)
Mental Health = 48.9 (+ 11.5)
Summary of Total Scores for each Dimension
Comparison of the study findings: Male & female
INTRODUCTION
Increased availability of ART reduced HIV-related morbidity and
mortality
Taking lifetime treatment with potential adverse effects may affect
their HRQOL
“Improving patient’s QOL” is one of the therapeutic objectives of
HIV treatment
HIV- Initially known as “slim disease” with excessive wt loss. But
now the problem is weight gain & associated complications
“Screening for nutritional status and assessment of dietary intake
should be included routinely in HIV treatment and care of adults
and children” (WHO April 2005)
Male
Female
Physical Health Summary Score
53.3
49.9
Mental Health Summary Score
49.4
46.9
Under Wt (BMI < 20 Kg/m²)
2.5 %
18.2 %
Desirable Wt (BMI Kg/m²)
53.7 %
36.4 %
Over Wt (BMI > Kg/m²)
31.3 %
22.7 %
Obese (BMI > 30 Kg/m²)
12.5 %
Low Risk of Malnutrition
95 %
77.3 %
Medium Risk of malnutrition
13.6 %
High Risk of malnutrition
9.1 %
AIMS
To assess:
HRQOL of patients with HIV infection living in Ireland
The prevalence of malnutrition among the patients with HIV
infection in Ireland
METHODS
Administrative, Demographic & Clinical data are collected from
102 Patients and their Clinical records using CRF
HRQOL data are collected using Medical Outcomes Study HIV
(MOS-HIV) Survey Questionnaire
Patient’s BMI, unplanned weight loss and history of lack of food
intake are recorded from patients and Clinical records.
Nutritional status and prevalence of malnutrition is assessed using
Malnutrition Universal Screening Tool (MUST). This is a five-step
screening tool to identify adults, who are malnourished, at risk of
malnutrition, or obese. It also includes management guidelines
which can be used to develop a care plan.
SUMMARY
Patients with HIV infection reported an average PHS Score of 52.5 and MHS Score of 48.9 (Total score ranges from 0-100, higher the score better the quality of life).
Females reported a lower PHS Score (49.9) and MHS Score (46.9) compared to males. PHS Score difference was statistically significant (p < 0.02).
Screening with MUST identified that only 50% of the patients have normal BMI (20-25 Kg/m²) and 44% are over weight or obese.
53.7% of males had normal BMI whereas only 36.4% of females had normal BMI
Females have higher rate of medium risk (13.6 %) and high risk (9.1 %) of malnutrition compared to males.
CONCLUSION
Patients with HIV infection have similar PHS to the general population. MHS is lower than general population
Females had both lower PHS and MHS than males
This study identified potential physical and mental health issues in female patients.
The prevalence of malnutrition especially in females highlights the need for screening and management of nutritional issues and associated complications in HIV patients
REFERENCES
Wu, A. W., Ed. (1999). MOS-HIV Health Survey Users Manual.
John Hopkins University.
2. Elia, M. (2003). The MUST Report. National screening of adults:
a multidisciplinary responsibility. Executive Summary,
Malnutrition Advisory Group; A Standing Committee of BAPEN.