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Bullous pyoderma gangrenosum induced by a local injection of guadecitabine in a patient with acute myeloid leukemia  Yi-Chun Hou  Dermatologica Sinica 

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Presentation on theme: "Bullous pyoderma gangrenosum induced by a local injection of guadecitabine in a patient with acute myeloid leukemia  Yi-Chun Hou  Dermatologica Sinica "— Presentation transcript:

1 Bullous pyoderma gangrenosum induced by a local injection of guadecitabine in a patient with acute myeloid leukemia  Yi-Chun Hou  Dermatologica Sinica  DOI: /j.dsi Copyright © Terms and Conditions

2 Fig. 1 (A) Four large hemorrhagic bullae at sites of guadecitabine injections. (B) Central necrosis with an areola of erythema and edema. (C) Histopathologic features a subepidermal blister with diffuse dermal neutrophil infiltration (hematoxylin and eosin stain, 40×). (D) High-power view (hematoxylin and eosin stain, 200×). Pyoderma gangrenosum recurred at a (E) previous lesion site and (F) new injection site (arrow) a few days after guadecitabine re-challenge. These lesions promptly responded to methylprednisolone. Dermatologica Sinica DOI: ( /j.dsi ) Copyright © Terms and Conditions


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