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Irinotecan, Carboplatin, and Imatinib in Untreated Extensive-Stage Small-Cell Lung Cancer: A Phase II Trial of the Minnie Pearl Cancer Research Network 

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Presentation on theme: "Irinotecan, Carboplatin, and Imatinib in Untreated Extensive-Stage Small-Cell Lung Cancer: A Phase II Trial of the Minnie Pearl Cancer Research Network "— Presentation transcript:

1 Irinotecan, Carboplatin, and Imatinib in Untreated Extensive-Stage Small-Cell Lung Cancer: A Phase II Trial of the Minnie Pearl Cancer Research Network  David R. Spigel, MD, John D. Hainsworth, MD, Lisa Simons, Christina Meng, Howard A. Burris, MD, Denise A. Yardley, MD, Richard Grapski, MD, Marshall Schreeder, MD, Padmaja V. Mallidi, MD, F Anthony Greco, MD  Journal of Thoracic Oncology  Volume 2, Issue 9, Pages (September 2007) DOI: /JTO.0b013e b7 Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Progression-free survival (PFS) for the entire group (n = 68). Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e b7) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Overall survival for the entire group (n = 68). CI, confidence interval; pts, patients. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e b7) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Progression-free survival (PFS) by KIT expression: positive or negative. pt, patient. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e b7) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 Overall survival by KIT expression: positive or negative. pt, patient. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e b7) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

6 FIGURE 5 Progression-free survival (PFS) by KIT expression: 0, 1+, 2+, 3+. pt, patient. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e b7) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

7 FIGURE 6 Overall survival by KIT expression: 0, 1+, 2+, 3+. pts. patients. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e b7) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions


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