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Volume 61, Issue 1, Pages (January 2002)

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Presentation on theme: "Volume 61, Issue 1, Pages (January 2002)"— Presentation transcript:

1 Volume 61, Issue 1, Pages 61-67 (January 2002)
Role of TGF-β1 in renal parenchymal scarring following childhood urinary tract infection  Shirley A. Cotton, Rasheed A. Gbadegesin, Shelley Williams, Paul E.C. Brenchley, Nicholas J.A. Webb  Kidney International  Volume 61, Issue 1, Pages (January 2002) DOI: /j x Copyright © 2002 International Society of Nephrology Terms and Conditions

2 Figure 1 Transforming growth factor-β1 (TGF-β1) production by peripheral blood mononuclear cells (PBMC); a comparison of TGF-β genotype. TGF-β1 production was significantly higher in those patients with a GG -800 TGF-β1 genotype than those with a GA genotype. The thick horizontal bar denotes the median, and whiskers show the interquartile range. P = by the Mann-Whitney U test. Kidney International  , 61-67DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

3 Figure 2 TGF-β1 production by PBMC; a comparison of the renal parenchymal scarring (RPS) versus the no scarring (NS) groups of children. There was no significant difference in PBMC TGF-β1 production between those patients who had not developed RPS (NS) and those who had developed RPS. The thick horizontal bar denotes the median, and whiskers show the interquartile range. P = by the Mann-Whitney U test. Kidney International  , 61-67DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions


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