1. A 45-SNP genetic risk score is increased in early-onset coronary artery disease but independent of familial disease clustering 
Morten K. Christiansen, Mette Nyegaard, Lisbeth N. Pedersen, Sanne B. Larsen, Morten Würtz, Jakob Hjort, Steen D. Kristensen, Henrik K. Jensen 
Atherosclerosis 
Volume 257, Pages (February 2017)
DOI: /j.atherosclerosis
Copyright © 2017 Elsevier B.V. Terms and Conditions

2. Fig. 1
Relationship between the genetic risk score (GRS) and age of coronary artery disease (CAD) onset. (A) Genetic risk scores (GRS) in healthy controls, late-onset CAD patients, and early-onset CAD patients. Yellow, red, and green lines indicate mean ± one standard deviation. Overall p <  *Healthy controls vs. late-onset CAD: p =  **Late-onset CAD vs. early-onset CAD: p = 0.02. ***Healthy controls vs. early-onset CAD: p <  (B) GRS vs. age at CAD onset. R2 = 1.4% for the regression line. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Atherosclerosis  , DOI: ( /j.atherosclerosis )
Copyright © 2017 Elsevier B.V. Terms and Conditions

3. Fig. 2
Relationship between the genetic risk score (GRS) and familial clustering in early-onset coronary artery disease (CAD). (A) GRS according to the stratified log-rank family score (SLFS) tertiles. Overall p =  Yellow, red, and green lines indicate mean ± one standard deviation. (B) GRS vs. SLFS. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Atherosclerosis  , DOI: ( /j.atherosclerosis )
Copyright © 2017 Elsevier B.V. Terms and Conditions

4. Fig. s1
Atherosclerosis  , DOI: ( /j.atherosclerosis )
Copyright © 2017 Elsevier B.V. Terms and Conditions

5. Fig. s2
Atherosclerosis  , DOI: ( /j.atherosclerosis )
Copyright © 2017 Elsevier B.V. Terms and Conditions