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The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: A systematic review and meta-analysis  Linda L.D. Zhong, Hai-Yong.

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Presentation on theme: "The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: A systematic review and meta-analysis  Linda L.D. Zhong, Hai-Yong."— Presentation transcript:

1 The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: A systematic review and meta-analysis  Linda L.D. Zhong, Hai-Yong Chen, William C.S. Cho, Xiao-ming Meng, Yao Tong  Complementary Therapies in Medicine  Volume 20, Issue 4, Pages (August 2012) DOI: /j.ctim Copyright © 2012 Elsevier Ltd Terms and Conditions

2 Figure 1 Flow diagram of study selection. CHM: Chinese herbal medicine. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2012 Elsevier Ltd Terms and Conditions

3 Figure 2 Overall survival estimated from meta-analysis of pairwise comparisons in patients with Chinese herbal medicine (CHM, treatment group) versus patients without CHM (control group): (A) number of patients with survival >1 year; (B) number of patients with survival >3 years. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2012 Elsevier Ltd Terms and Conditions

4 Figure 3 Overall efficacy estimated from meta-analysis of pairwise comparisons in patients with Chinese herbal medicine (CHM, treatment group) versus patients without CHM (control group): (A) number of patients with complete response (CR) or partial response (PR); (B) number of patients with progressive disease (PD); (C) number of patients with non-deterioration Karnofsky performance score (KPS). Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2012 Elsevier Ltd Terms and Conditions

5 Figure 4 Immune effect estimated from meta-analysis of pairwise comparisons in patients with Chinese herbal medicine (CHM, treatment group) versus patients without CHM (control group): (A) mean difference between pre- and post-treatment CD3 T cell levels of patients treated by FOLFOX; (B) mean difference between pre- and post-treatment CD4 T cell levels of patients treated by chemotherapy (CMT); (C) mean difference between pre- and post-treatment CD4/CD8 ratios of patients treated by chemotherapy (CMT). Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2012 Elsevier Ltd Terms and Conditions

6 Figure 5 Reduction of adverse effects estimated from meta-analysis of pairwise comparisons in patients with Chinese herbal medicine (CHM, treatment group) versus patients without CHM (control group): (A) number of patients with nausea and vomiting treated by 5-FU/CF; (B) number of patients with appetite loss treated by chemotherapy (CMT); (C) number of patients with diarrhea treated by FOLFOX or 5-FU/CF. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2012 Elsevier Ltd Terms and Conditions


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