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Usefulness of oral beclometasone dipropionate in the treatment of active ulcerative colitis in clinical practice: The RECLICU Study  Tiago Nunes, Manuel.

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Presentation on theme: "Usefulness of oral beclometasone dipropionate in the treatment of active ulcerative colitis in clinical practice: The RECLICU Study  Tiago Nunes, Manuel."— Presentation transcript:

1 Usefulness of oral beclometasone dipropionate in the treatment of active ulcerative colitis in clinical practice: The RECLICU Study  Tiago Nunes, Manuel Barreiro-de Acosta, Pilar Nos, Ignacio Marin-Jiménez, Fernando Bermejo, Daniel Ceballos, Eva Iglesias, Silvia Gomez-Senent, Yolanda Torres, Angel Ponferrada, José A. Arevalo, Vicent Hernandez, Xavier Calvet, Daniel Ginard, David Monfort, Maria Chaparro, Noemi Manceñido, Mercedes Domínguez-Antonaya, César Villalón, José L. Perez-Calle, Carmen Muñoz, Henar Nuñez, Daniel Carpio, Roberto Aramendiz, Luis Bujanda, Silvia Estrada-Oncins, Carlos Hermida, Jesus Barrio, Mª Begoña Casis, Ma Carmen Dueñas-Sadornil, Luis Fernández, Mª Mar Calvo-Cenizo, Belen Botella, Ruth de Francisco, Edgar Ayala, Miquel Sans  Journal of Crohn's and Colitis  Volume 4, Issue 6, Pages (December 2010) DOI: /j.crohns Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

2 Figure 1 BDP dose and treatment duration. A) Percentage of patients treated with each BDP dose. B) Percentage of patients according to duration of BDP treatment. Journal of Crohn's and Colitis 2010 4, DOI: ( /j.crohns ) Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

3 Figure 2 Other treatment changes at BDP start. Each bar represents the percentage of patients in which treatment was modified when BDP was started. Journal of Crohn's and Colitis 2010 4, DOI: ( /j.crohns ) Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

4 Figure 3 BDP efficacy. A) Global efficacy of BDP treatment: each bar represents the percentage of patients achieving remission, response or failure under BDP treatment; B) Mayo score pre/post BDP treatment: box plot graphic displays the distribution of pMS before and after BDP treatment. Journal of Crohn's and Colitis 2010 4, DOI: ( /j.crohns ) Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

5 Figure 4 Factors influencing BDP-induced remission. Bars represent the percentage of patients that achieved remission under BDP treatment, according to UC severity (A), extension (B), maintenance treatment (C) and changes in treatment (D). Journal of Crohn's and Colitis 2010 4, DOI: ( /j.crohns ) Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

6 Figure 5 Efficacy of BDP treatment according to dose and therapy duration. Bars represent the percentage of patients that achieved remission, response or failure according to A) BDP dose and B) treatment duration. Journal of Crohn's and Colitis 2010 4, DOI: ( /j.crohns ) Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

7 Figure 6 Rescue therapy after BDP treatment. Each bar represents the percentage of patients receiving different medical rescue therapies or requiring colectomy. Journal of Crohn's and Colitis 2010 4, DOI: ( /j.crohns ) Copyright © 2010 European Crohn's and Colitis Organisation Terms and Conditions

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