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Tracheobronchial Pulmonary Disease Associated With Pyoderma Gangrenosum  Soichiro Kanoh, MD, PhD, Hideo Kobayashi, MD, PhD, Ken Sato, MD, PhD, Kazuo Motoyoshi,

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1 Tracheobronchial Pulmonary Disease Associated With Pyoderma Gangrenosum 
Soichiro Kanoh, MD, PhD, Hideo Kobayashi, MD, PhD, Ken Sato, MD, PhD, Kazuo Motoyoshi, MD, PhD, Shinsuke Aida, MD, PhD  Mayo Clinic Proceedings  Volume 84, Issue 6, Pages (June 2009) DOI: / Copyright © 2009 Mayo Foundation for Medical Education and Research Terms and Conditions

2 FIGURE 1 Flexible bronchoscopy at the level of the trachea (left) and bifurcation of left upper and lower lobe (right) revealed multiple yellowish-white endobronchial polypoid nodules and mucosal redness. The polypoid lesions had an irregular, necrotic, and friable surface with lobulation. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2009 Mayo Foundation for Medical Education and Research Terms and Conditions

3 FIGURE 2 Biopsy specimen from bronchial polypoid nodules showed actively inflamed granulation tissue with infiltration by numerous neutrophils and lymphoplasma cells with necrosis. No vasculitis or granulomas were seen (hematoxylin-eosin, original magnificatio×40). Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2009 Mayo Foundation for Medical Education and Research Terms and Conditions


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