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Lucio Lombardo, Monica Foti, Olga Ruggia, Andrea Chiecchio 

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Presentation on theme: "Lucio Lombardo, Monica Foti, Olga Ruggia, Andrea Chiecchio "— Presentation transcript:

1 Increased Incidence of Small Intestinal Bacterial Overgrowth During Proton Pump Inhibitor Therapy 
Lucio Lombardo, Monica Foti, Olga Ruggia, Andrea Chiecchio  Clinical Gastroenterology and Hepatology  Volume 8, Issue 6, Pages (June 2010) DOI: /j.cgh Copyright © 2010 AGA Institute Terms and Conditions

2 Figure 1 Prevalence of small intestinal bacterial overgrowth (mean value ± standard deviation), as assessed by glucose hydrogen breath test. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

3 Figure 2 Age distribution (mean value ± standard deviation) in PPI and IBS GHBT-positive patients. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

4 Figure 3 Prevalence of small intestinal bacterial overgrowth (mean value ± standard deviation) in PPI-treated patients according to the duration of therapy. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

5 Figure 4 Severity of symptoms (mean value ± standard deviation) assessed by symptom index score in different classes of duration of PPI therapy (months). Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

6 Figure 5 Types of SIBO-related symptoms in PPI and IBS groups. B, bloating; C, constipation; D, diarrhea; MA, macrocytic/megaloblastic anemia (hemoglobin <11 g/dL; mean globular volume >98 fmol; red blood cell count <4,000,000/μL); P, lower abdominal pain (of any degree during the last month); WL, weight loss (>10% during the last 6 months). Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions


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