Presentation is loading. Please wait.

Presentation is loading. Please wait.

Treatment of attacks with plasma-derived C1-inhibitor concentrate in pediatric hereditary angioedema patients  Henriette Farkas, MD, PhD, DSc, Dorottya.

Published byEnikő Kovács Modified over 6 years ago

Similar presentations

Presentation on theme: "Treatment of attacks with plasma-derived C1-inhibitor concentrate in pediatric hereditary angioedema patients  Henriette Farkas, MD, PhD, DSc, Dorottya."— Presentation transcript:

1 Treatment of attacks with plasma-derived C1-inhibitor concentrate in pediatric hereditary angioedema patients  Henriette Farkas, MD, PhD, DSc, Dorottya Csuka, MSc, Zsuzsanna Zotter, MD, Erika Szabó, MD, Ibolya Czaller, MD, Lilian Varga, PhD, János Fejes, MD, George Füst, PhD, DSc, George Harmat, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 131, Issue 3, Pages e5 (March 2013) DOI: /j.jaci Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Age at the first onset of HAE symptoms, at the diagnosis of HAE, and at the first administration of the pdC1-INH concentrate (years). Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Time to initial relief of symptoms (A) and time to complete resolution (B) of symptoms after the administration of the pdC1-INH concentrate (Berinert, CSL Behring) (minutes). Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig E1 The distribution of attacks by location. A, All attacks (n = 1392) observed during the study. B, Attacks (n = 152) treated with the pdC1-INH concentrate (Berinert, CSL Behring) during the study. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig E2 Analysis of the relationship between the number of vials of the pdC1-INH concentrate (Berinert, CSL Behring) received and the titers of antibodies to C1-INH. Two groups (“1-3 vials of pdC1-INH” and “>3 vials of pdC1-INH”) were created by dividing the study population into 2 subsets according to median per capita pdC1-INH consumption during the observational period. Start, time of diagnosis (ie, the beginning of the observational period). End, the year when the patient turned 18 years old (ie, the end of the observational period). Horizontal lines represent the upper limit of the normal range for each antibody. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Download ppt "Treatment of attacks with plasma-derived C1-inhibitor concentrate in pediatric hereditary angioedema patients  Henriette Farkas, MD, PhD, DSc, Dorottya."

Similar presentations

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,
A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,
Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,

Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.

Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.
Hereditary angioedema: A decade of human C1-inhibitor concentrate therapy  Henriette Farkas, MD, PhD, DSc, László Jakab, MD, György Temesszentandrási,

Hereditary angioedema: A decade of human C1-inhibitor concentrate therapy  Henriette Farkas, MD, PhD, DSc, László Jakab, MD, György Temesszentandrási,
D-dimer: A biomarker for antihistamine-resistant chronic urticaria

D-dimer: A biomarker for antihistamine-resistant chronic urticaria
Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS 

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS 
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
What drives prescription patterns in pediatric asthma management?

What drives prescription patterns in pediatric asthma management?
Alveolar nitric oxide and asthma control in mild untreated asthma

Alveolar nitric oxide and asthma control in mild untreated asthma
Tetanus immunity after diphtheria, tetanus toxoids, and acellular pertussis vaccination in children with clinically stable HIV infection  Howard M. Rosenblatt,

Tetanus immunity after diphtheria, tetanus toxoids, and acellular pertussis vaccination in children with clinically stable HIV infection  Howard M. Rosenblatt,
Erika Kajdácsi, MSc, Péter K

Erika Kajdácsi, MSc, Péter K
Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks  Timothy J. Craig, MD, Robyn J. Levy,

Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks  Timothy J. Craig, MD, Robyn J. Levy,
Allergen immunotherapy: A practice parameter third update

Allergen immunotherapy: A practice parameter third update
Fatty acids, inflammation, and asthma

Fatty acids, inflammation, and asthma
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Recombinant Human C1-Esterase Inhibitor to Treat Acute Hereditary Angioedema Attacks in Adolescents  James W. Baker, MD, Avner Reshef, MD, Dumitru Moldovan,

Recombinant Human C1-Esterase Inhibitor to Treat Acute Hereditary Angioedema Attacks in Adolescents  James W. Baker, MD, Avner Reshef, MD, Dumitru Moldovan,
Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks  Timothy J. Craig, MD, Robyn J. Levy,

Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks  Timothy J. Craig, MD, Robyn J. Levy,
Subcutaneous Icatibant for the Treatment of Hereditary Angioedema Attacks: Comparison of Home Self-Administration with Administration at a Medical Facility 

Subcutaneous Icatibant for the Treatment of Hereditary Angioedema Attacks: Comparison of Home Self-Administration with Administration at a Medical Facility 

Similar presentations

Ads by Google