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Chad G. Rusthoven, MD, Christine F. Lauro, MD, Brian D

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1 Stereotactic body radiation therapy (SBRT) for liver metastases: A clinical review 
Chad G. Rusthoven, MD, Christine F. Lauro, MD, Brian D. Kavanagh, MD, Tracey E. Schefter, MD  Seminars in Colon and Rectal Surgery  Volume 25, Issue 1, Pages (March 2014) DOI: /j.scrs Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Fig Axial and coronal images from a representative liver SBRT plan. Legend: A case of stage IV esophageal adenocarcinoma with a large, inoperable liver metastasis (4.1 × 4.5 × 3.4cm3). The red line corresponds to the 100% prescription isodose line (in this case 50Gy delivered in 5 fractions) and conforms tightly to the tumor target volume outlined in black. The yellow line corresponds to the 60% isodose line (in this case 30Gy) demonstrating rapid dose fall-off. The central darker red line represents an intended “hot spot” (in this case 62.5Gy which represents the 125% isodose line) for enhanced cell kill at the tumor's more resistant hypoxic center. Seminars in Colon and Rectal Surgery  , 48-52DOI: ( /j.scrs ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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