1. U #
19 year old female
Artheritis with increased creatinine, proteinuria, hematuria.
? Lupus

2. 21yrs old female    Presented with arthralgias associated with an elevated serum creatinine. Symptoms began immediately after a (second) therapeutic abortion Creatinine 189 U/A +3 protein ,WBC  ,RBC 11-25, Protein/Cr  227 mg/mmole, Albumin 19 Hb 79   plat 168 WBC 3.9 Anti DNA + ANA  + C3  &    C4  Low

3. IF
IgG- Moderate to strong coarsely granular capillary loop staining, moderate granular peritubular staining
IgA- Moderate coarsely granular capillary loop staining
IgM- Negative
C3- Moderate coarsely granular capillary loop staining, moderate granular peritubular staining
C1q- Moderate coarsely granular capillary loop staining, mild to moderate granular peritubular staining
Kappa- Mild to moderate coarsely granular capillary loop staining, mild to moderate granular peritubular staining
Lambda- Same as kappa
Fibrin- Mild to moderate interstitial staining
Albumin- Mild to moderate hyaline droplet change in tubular cytoplasm

4. IgG

5. IgG

6. IgA

7. C3

8. C3

9. Clq

10. Clq

11. Kappa

12. Kappa

13. Lambda

14. Lambda

15. Fibrin

16. Albumin

21. Diagnosis: Renal Biopsy: Diffuse global proliferative lupus nephritis (Class IV-G (A), 2003 ISN/RPS Classification) with moderate activity and mild chronicity.