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Optical coherence tomography imaging of non-melanoma skin cancer undergoing photodynamic therapy reveals subclinical residual lesions  L. Themstrup, C.A.

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Presentation on theme: "Optical coherence tomography imaging of non-melanoma skin cancer undergoing photodynamic therapy reveals subclinical residual lesions  L. Themstrup, C.A."— Presentation transcript:

1 Optical coherence tomography imaging of non-melanoma skin cancer undergoing photodynamic therapy reveals subclinical residual lesions  L. Themstrup, C.A. Banzhaf, M. Mogensen, G.B.E. Jemec  Photodiagnosis and Photodynamic Therapy  Volume 11, Issue 1, Pages 7-12 (March 2014) DOI: /j.pdpdt Copyright © 2013 Elsevier B.V. Terms and Conditions

2 Fig. 1 Superficial basal cell carcinoma (BCC(s)) located above the eyebrow (case no. 17). (a) Clinical photo of lesion (white arrow). (b) Optical coherence tomography (OCT) image (original OCT image dimension: 5×2mm) of lesion displaying disruption of normal layering (white vertical line) and tumour lobules (white arrows) with areflective cores representing central necrosis (white circles). (c) OCT image of lesion taken right after 1st methyl aminolaevulinate photodynamic therapy treatment. The image has a homogeneous texture, a blurred appearance and the lesion is not obvious. (d) OCT image at a 3-month follow-up. The dermoepidermal junction has been fully restored (white arrows), sign of complete remission. Photodiagnosis and Photodynamic Therapy  , 7-12DOI: ( /j.pdpdt ) Copyright © 2013 Elsevier B.V. Terms and Conditions

3 Fig. 2 Superficial basal cell carcinoma (BCC(s)) located on the tip of the nose (case no. 9). (a1) Clinical photo of lesion. (b1) Optical coherence tomography (OCT) image (original OCT image dimension: 5×2mm) of lesion displaying disruption of normal layering (white vertical lines) and a tumour lobule (white arrows). (a2) Clinical photo of lesion right after the 2nd session of methyl aminolaevulinate photo dynamic therapy (MAL-PDT). (b2) OCT image of lesion right after the 2nd session of MAL-PDT. The image has a homogeneous texture, a blurred appearance and the lesion is not obvious. (a3) Clinical photo of the treated lesion (white circle) 3 months after the last MAL-PDT session. (c3) OCT image at 3-months follow-up. The image shows disruption of layering and thickening of epidermis (white vertical lines) indicating a partial response to MAL-PDT treatment. The white arrows point to the dermoepidermal junction. Photodiagnosis and Photodynamic Therapy  , 7-12DOI: ( /j.pdpdt ) Copyright © 2013 Elsevier B.V. Terms and Conditions


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