1. From: Systemic Treatment With Glutathione PEGylated Liposomal Methylprednisolone (2B3-201) Improves Therapeutic Efficacy in a Model of Ocular Inflammation
Invest. Ophthalmol. Vis. Sci ;55(4): doi: /iovs
Figure Legend:
Effect of intravenous dosing of 2B3-201 on EAU. (A) Incidence of clinical EAU in rats. (B) Clinical signs of uveitis in rats treated with vehicle (0.9% sodium chloride, in black), rats receiving one dose of 2B3-201 at day 10 (in red), rats treated with two doses of free MPhs (in green), or rats treated with 2B3-201 at days 14 and 18 (in blue) upon disease induction. Data represent the mean clinical scores ± SEM of 24 eyes per group. (C) Total disease burden integrated over time per individual animal (which is the cumulative EAU score per animal). *P < 0.05, **P < 0.01 by Mann-Whitney U test.
Date of download: 10/27/2017
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