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Earlier diagnosis of lung cancer
Dr Neal Navani MA MSc PhD FRCP Consultant Respiratory Physician, UCLH Co-clinical lead, NLCA @LungConsultant
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IASLC Stage grouping for TNM 8
Earlier stage improves survival;
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Millimeters matter
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Olesen et al BJC 2009
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Diagnosing lung cancer at earlier stage -1
Engage with primary care Promote Be Clear On Cancer campaign CXR and CT capacity Ironmonger BJC 2015
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Diagnosing lung cancer at earlier stage -1
Promote Be Clear On Cancer campaign May to Late August 2017
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Diagnosing lung cancer at earlier stage -2
Open access / self-referral for CXR Advertising campaign Community education 55% increase in CXRs in 2011 vs previous years (Callister et al.) Reduced emergency admissions GP direct access to CT Clinical risk assessment tools
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Diagnosing lung cancer at earlier stage - 3
Dysplastic airway lesions Severe dysplasia / CIS on airway biopsy or at resection margin Autofluorescence bronchoscopy Surveillance for progression to invasive carcinoma
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Diagnosing lung cancer earlier
Follow available guidelines Biopsy lymph nodes vs primary Nodule clinics / BTS guideline Fewer scans National optimal lung cancer pathway
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Diagnosing lung cancer earlier
Lung-BOOST: pts Stage I - IIIA Navani et al Lancet Resp Med 2015
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Diagnosing lung cancer earlier
Navani et al Lancet Resp Med 2015
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Diagnosing lung cancer earlier
Co-morbidity management Increase biopsy rate Increase active treatment rates Increase radical treatment rates Reduce decline in PS
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Summary
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@LungConsultant n.navani@ucl.ac.uk
Acknowledgments UCLH Lung cancer MDT UCL Respiratory NLCA team Mat Callister, David Baldwin @LungConsultant
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