1. Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal
Blood Purif 2017;44: DOI: /
Fig. 1. Relationship between the mass removal rate and clearance for a high-efficiency dialysis modality used for end-stage renal disease (left) and CRRT used for AKI (right). Adapted from [29]. Reprinted with permission from [29].
© 2017 S. Karger AG, Basel

2. Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal
Blood Purif 2017;44: DOI: /
Fig. 2. Survival as a function of baseline illness severity in AKI patients treated with conventional hemodialysis. CCF, Cleveland Clinic Foundation. Reprinted with permission from [4].
© 2017 S. Karger AG, Basel

3. Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal
Blood Purif 2017;44: DOI: /
Fig. 3. Solute clearance as a function of ultrafiltration rate in isovolemic predilution hemofiltration. Urea clearance was measured at ultrafiltration rates of 1.2, 2.4, and 3.6 L/h. The blood flow rate was 200 mL/min. Reprinted with permission from the publisher [74].
© 2017 S. Karger AG, Basel

4. Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal
Blood Purif 2017;44: DOI: /
Fig. 4. Estimates for the decrement in delivered Kt/V due to treatment downtime and fluid overload during CRRT. The influences of downtime ranging from 0 to 6 h per day (a) and percent fluid overload values ranging from 0 to 20% (along with fluid deficit of 10%; b) are shown. Reprinted with permission from [83].
© 2017 S. Karger AG, Basel

5. Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal
Blood Purif 2017;44: DOI: /
Table 1. Treatment parameters in trial comparing different regimens of conventional hemodialysis patterns for patients with AKI*
© 2017 S. Karger AG, Basel

6. Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal
Blood Purif 2017;44: DOI: /
Table 2. Urea kinetic parameters for critically ill, acute kidney injury patients treated with continuous venovenous hemofiltration*
© 2017 S. Karger AG, Basel