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Date of download: 10/23/2017 Copyright © ASME. All rights reserved.

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1 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Schematic of the model. A multiscale model for the collagen network is combined with a single-scale (macroscopic) model of the noncollagenous material. The initial state of the artery is described by radius Ri, wall thickness H, and open angle Θ.

2 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Simulation procedure: (a) initial, stress-free configuration with open angle; (b) the artery is closed to produce a hollow cylinder; (c) the artery is stretched axially by 30%; and (d) stretched artery is inflated to 150mmHg luminal pressure

3 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Pressure versus inner diameter for experimental (squares, Ref. ) and computed (solid) results

4 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Wall thickness versus pressure for experimental (squares, Ref. ) and computed (solid) results

5 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Distribution of fiber stretch ratio. The histogram shows the final distribution of fibers in an RVE after a macroscopic closure from 26deg open angle, extension to 55%, and inflation to 200mmHg.

6 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Collagen and matrix contributions to the circumferential stress. Results for 26deg open angle, 30% extension, and 200mmHg inflation. The noncollagenous matrix is in compression, while the collagen in tension.

7 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Schematic generation of collagen network

8 Date of download: 10/23/2017 Copyright © ASME. All rights reserved. From: Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls J Biomech Eng. 2007;129(4): doi: / Figure Legend: Local fiber coordinates in calculation of Ω. r is the directional vector of the fiber.


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