1. On Target? Do this on your Warm Up worksheet!
How does the information in DNA become the proteins that are responsible for a trait?
DNA  PROTEIN  TRAIT

2. For Today: Warm Up Notes Dances with Ribosomes Diagram
Objective: I can use an analogy of the classroom as a cell to explain transcription/translation.

3. Part: Represents: Function: Hallway outside White Cards Purple Blob
Green Cards
Balloons
Classroom
Purple Cards
(DNA overview)
Hall outside = nucleus
White cards= mRNA
Purple blob = ribosome
Green cards = tRNA
Balloons = amino acids
Classroom = cytoplasm
Pink cards = DNA

4. Ribosomes = purple blob
Amino acids = balloons
DNA=
Purple cards
tRNA = green cards
mRNA = white cards
Nucleus = hallway
Ribosomes = purple blob
Dances with Ribosomes Directions:
Pink DNA strand is out in the hallway (because it stays in the nucleus). Students should use the white mRNA cards to make a mRNA strand in order in the hallway. Then, students will enter the classroom in order and place the mRNA on the back counter and tape it together. (23 mRNA cards, so 23 students will be entering the classroom).
2-3 Students will be manning the ribosome. They will pick up the connected mRNA and run it through the ribosome, stopping at 3 letters at a time. The class will recognize which green tRNA card matches with it, and then which amino acid matches. A student with a matching green tRNA card will find the corresponding colored balloon, and then bring that balloon to the ribosome and tape the balloon onto the green string that is connecting the proteins together.
Cytoplasm = classroom
space
Cell = 3rd floor of school!

5. Dances With Ribosomes
In this activity we will be role-playing the processes of PROTEIN SYNTHESIS. Example: Zr9B-zLsA&t=101s
(Dances with ribosomes example)

6. Dances with Ribosomes
There is a purple strand of DNA on the wall in the hallway. Pick up a white mRNA card and line up the mRNA in order corresponding to the DNA in the hallway (There are only 23 mRNA cards, so not all students will be in the hallway. If you are not in the hallway, gather in the back to help your classmates tape the mRNA together)
2. Once the mRNA is in order, you will enter the classroom in a single file line and place your mRNA on the back counter to be taped in order.

7. Dances with Ribosomes
2-3 Students will be manning the ribosome. They will pick up the connected mRNA and run it through the ribosome, stopping at 3 letters at a time. The class will recognize which green tRNA card matches with it, and then which amino acid matches.
A student with a matching green tRNA card will find the corresponding colored balloon, and then bring that balloon to the ribosome and tape the balloon onto the green string that is connecting the proteins together.

8. Amino acid Codons Balloon Lys AAA AAG Blue Leu UUA UUG CUA CUC CUG CUU
Green
Phe
UUC UUU
yellow
Asp
GAC GAU
red
DNA: AAA GAC CTT TTC CTT AAA AAA GAC TTC GAC TTC TTC AAA GAC TTC AAA GAC TTC TTC AAA CTT CTT CTT
mNA: UUU CUG GAA AAG GAA UUU UUU CUG AAG CUG AAG AAG UUU CUG AAG UUU CUG AAG AAG UUU GAA GAA GAA
tRNA: AAA GAC CUU UUC CUU AAA AAA GAC UUC GAC UUC UUC AAA GAC UUC AAA GAC UUC UUC AAA CUU CUU CUU
amino: lys asp leu phe leu lys lys asp phe asp phe phe lys asp phe lys asp phe phe lys leu leu leu
Color: B R G Y G B B R Y R Y Y B R Y B R Y Y B G G G

9. CLEAN UP Balloons go back up to the front of the room under the screen
Put green and white cards in the baskets and bring them up to Ms. G

10. EXIT TICKET DNA -- A T T C G C AAA TTC mRNA-- tRNA— Amino acid--
Codons
Balloon
Lys
AAA AAG
Blue
Leu
UUA UUG
CUA CUC
CUG CUU
Green
Phe
UUC UUU
yellow
Asp
GAC GAU
red
ile
AUU
Arg
CGC
ATT CGC AAA TTC
UAA GCG UUU AAG
AUU CGC AAA UUG
Ile Arg Lys Leu

11. EXIT TICKET DNA -- A T T C G C C G C C G C mRNA-- tRNA— Amino acid--
Codons
Balloon
Lys
AAA AAG
Blue
Leu
UUA UUG
CUA CUC
CUG CUU
Green
Phe
UUC UUU
yellow
Asp
GAC GAU
red
ile
AUU
Arg
CGC
2nd Period
ATT CGC CGC CGC
UAA GCG GCG GCG
AUU CGC CGC CGC
Ile Arg Arg Arg