1. Pulmonary Circulation- THIS IS A REVIEW!!!!
______________ blood enters the lungs from ______ ventricle of heart through the Pulmonary ________.
Pulmonary trunk splits into left and right pulmonary arteries that enter the two lungs
The vessels become arterioles, capillaries, and venules.
Oxygenated blood returns to the left atrium in the Pulmonary _______.

2. Thoracic Cavity
Bound by __________ vertebrae dorsally, ______ & _____________ muscles laterally, the __________ ventrally, and the _____________caudally.
Mediastinum – area between lungs REVIEW!!!

3. Pleura- REVIEW!!!
Serous membrane that lines thoracic cavity and covers the lungs.
__________ layer covers the lungs
__________ layer lines the cavity
Space between the two pleural layers is filled with a small amount of pleural _________ to prevent friction. (same in abdomen, pericardium). Too much fluid is called an ______________.

4. Diaphragm Thin, dome-shaped sheet of skeletal muscle
Forms caudal boundary of thorax
Base of lungs lie directly on the cranial surface and the liver lies on the caudal surface
Important respiratory muscle
Dome-shaped when ___________
Flattens when it __________
Enlarges volume of thorax and aids inspiration

5. Process of Respiration
Pressure within the thorax is ____________ with respect to atmospheric pressure.
Pulls lungs tight against the thoracic wall
Flexible nature of lungs allows them to conform with shape of the thoracic wall.
Pleural fluid provides __________.
Lungs follow movements of thoracic wall
Negative intrathoracic pressure helps draw blood through ________ in the mediastinum and into atria

6. Pneumothorax
Leakage of air into thorax → Loss of negative pressure in lungs
(causes “collapsed lung”)
Causes:
Penetrating wound of chest
Rupture of alveoli Rx
Remedy cause
Remove air from thorax
Needle/syringe (aka ____________________)
Chest tube

7. Inspiration is the process of drawing air into lungs (inhalation)
Results from increasing volume of thoracic cavity by inspiratory muscles
Main inspiratory muscles: ___________ and ____________ intercostal muscles
Expiration is the process of pushing air out of lungs (exhalation)
Results from decrease in size of thoracic cavity
Main expiratory muscles: ___________ intercostal muscles and ____________ muscles

8. ___________ volume – volume of air inspired and expired during one breath.
Varies according to body’s needs.
Smaller when animal is at rest and larger when excited and active.
__________ volume – volume of air inspired and expired during one minute.
Calculated by multiplying the tidal volume by breaths per minute.
__________ volume – volume of air remaining in the lungs after maximum expiration.
Residual volume always remains, lungs will never be completely emptied of air.
Respiratory Volumes

9. Alveolar Gas Exchange- REVIEW!!
Simple _________ of gas molecules from areas of _____ concentration to areas of _____ concentration.
_____ diffuses from the alveolar air into the blood of the alveolar capillary
_____diffuses from the blood into the alveolus

10. Even though all of the inspiratory and expiratory muscles are skeletal muscles under voluntary control, breathing does not require a conscious effort.
Breathing is controlled by an area in the _________ ___________ of the brain stem known as the Respiratory Center.
Directs timing and strength of contraction
Can be consciously controlled for brief periods.
Respiratory Center

11. Mechanical Control System
__________ receptors in the lungs set limits on routine resting inspiration and expiration.
Respiratory center sends out nerve impulses when lungs inflate to a certain point
Stops muscle contractions that produce inspiration and starts contractions to produce expiration
Another set of nerve impulses sent when lungs deflate sufficiently
Stops expiration and starts the process of inspiration again

12. Chemical Control System
Adjusts normal rhythmic breathing pattern produced by mechanical control system
Chemical (peripheral) receptors in carotid artery and aorta monitor blood _____, ____, and ____.
Central chemical receptors are located in the medulla oblongata.

13. Chemical Control System
Blood level of CO2 and blood pH linked
__CO2 in blood and __blood pH triggers respiratory center to increase rate and depth of respiration
__CO2 in blood and __blood pH triggers respiratory center to decrease rate and depth of respiration
Chemical Control System

14. Chemical Control System
_______ - decrease in blood O2 level
Slight hypoxia triggers respiratory center to increase the rate and depth of breathing
Severe hypoxia - neurons of the respiratory center can become so depressed that adequate nerve impulses cannot be sent to the respiratory muscles
Can cause breathing to decrease or stop completely
Chemical Control System