1. PGAM5 is important for A. mediating apoptosis
B. mediating multiple necrotic pathways
C. mitochondria fragmentation
D. formation of the RIP1/RIP3 complex in response to TNF treatment.
E. None of above

2. RIP3 is important for
A. mediating apoptosis B. mediating multiple necrotic pathways C. mitochondria fragmentation D. TNF-induced necrosis. E. None of above

3. MLKL is important for
A. mediating apoptosis B. mediating multiple necrotic pathways C. phosphorylation of DRP1 D. TNF-induced necrosis. E. None of above

4. PGAM5 is a protein on the plasma membrane a protein in the cytoplasm
a protein on mitochondria
a protein that translocates to mitochondria during necrosis.
None of above.

5. DRP1 is a protein on the plasma membrane a protein in the cytoplasm
a protein on mitochondria
a protein that translocates to mitochondria during necrosis.
None of above.

6. DRP1 needs to do the following to promote necrosis
be activated by PGAM5
be dephosphorylated
translocate to mitochondria.
have GTPase activity
All of above.