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Immunoassay for ethyl glucuronide in vitreous humor: A new tool for postmortem diagnostics of alcohol use  Juha Rainio, Johanna Kultti, Päivikki Kangastupa,

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Presentation on theme: "Immunoassay for ethyl glucuronide in vitreous humor: A new tool for postmortem diagnostics of alcohol use  Juha Rainio, Johanna Kultti, Päivikki Kangastupa,"— Presentation transcript:

1 Immunoassay for ethyl glucuronide in vitreous humor: A new tool for postmortem diagnostics of alcohol use  Juha Rainio, Johanna Kultti, Päivikki Kangastupa, Heidi Tuomi, Sanna Ahola, Pekka J. Karhunen, Anders Helander, Onni Niemelä  Forensic Science International  Volume 226, Issue 1, Pages (March 2013) DOI: /j.forsciint Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Vitreous humor ethyl glucuronide (VH-EtG) levels in cases with (4.23±4.85mg/l) or without (0.18±0.28mg/l) a documented history of excessive alcohol use, and in blood alcohol concentration (BAC) positive (4.45±2.56mg/l) and BAC negative (2.55±6.59mg/l) cases, as determined by an EtG immunoassay. The differences in VH-EtG concentrations between the two groups were statistically significant (p<0.001). Forensic Science International  , DOI: ( /j.forsciint ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Correlation between vitreous humor ethyl glucuronide (VH-EtG) immunoassay values and blood alcohol concentrations (BAC, ‰). At an EtG cut-off of 0.3mg/l, there were 12 patients who tested positive for VH-EtG despite testing negative for BAC. Forensic Science International  , DOI: ( /j.forsciint ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions


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