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Volume 105, Issue 4, Pages (April 1994)

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Presentation on theme: "Volume 105, Issue 4, Pages (April 1994)"— Presentation transcript:

1 Volume 105, Issue 4, Pages 1163-1170 (April 1994)
Control of Breathing and Respiratory Muscle Strength in Patients With Multiple Sclerosis  Claudio Tantucci, M.D., Maurizio Massucci, M.D., Roberto Piperno, M.D., Loris Betti, M.D., Vittorio Grassi, M.D., Carlo Augusto Sorbini, M.D.  CHEST  Volume 105, Issue 4, Pages (April 1994) DOI: /chest Copyright © 1994 The American College of Chest Physicians Terms and Conditions

2 FIGURE 1 Relationships between Pimax (left panel) and PEmax (right panel) measured at FRC and disability level (EDSS score). Maximal mouth pressures are expressed as percent of predicted. The little circles are individual data points and the continuous line is the regression line. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

3 FIGURE 2 Individual P0.1/PETCO2 slopes during CO2 rebreathing in patients with MS. The dashed area represents the P0.1/PETCO2 slope range (x- ± SEM) in the control group. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

4 FIGURE 3 Individual V ˙ e/PetCO2 slopes during CO2 rebreathing in patients with MS. The dashed area represents the V ˙ e/PetCO2 slope range (x-±SEM) in the control group. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

5 FIGURE 4 Relationship between P0.1 and V ˙ e (range, 10 to 40 L/m) in patients with MS (closed circles) and in control subjects (open circles). Circles and bars are means ± SEM. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

6 FIGURE 5 Relationships between Pimax and PEmax, as percent of predicted, and change of V ˙ e with increasing PetCO2 (Δ V ˙ e/ΔPetCO2). The inspiratory and expiratory muscle strength correlates directly with the ventilatory response to progressive hypercapnia. The small circles are individual data points and the continuous line is the regression line. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions


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