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Abscopal effect in recurrent colorectal cancer treated with carbon-ion radiation therapy: 2 case reports  Daniel K. Ebner, BS, Tadashi Kamada, MD, PhD,

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Presentation on theme: "Abscopal effect in recurrent colorectal cancer treated with carbon-ion radiation therapy: 2 case reports  Daniel K. Ebner, BS, Tadashi Kamada, MD, PhD,"— Presentation transcript:

1 Abscopal effect in recurrent colorectal cancer treated with carbon-ion radiation therapy: 2 case reports  Daniel K. Ebner, BS, Tadashi Kamada, MD, PhD, Shigeru Yamada, MD, PhD  Advances in Radiation Oncology  Volume 2, Issue 3, Pages (July 2017) DOI: /j.adro Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

2 Figure 1 Computed tomography (left) and positron emission tomography images displaying case 1's 35-mm left abdominal colorectal cancer recurrence (top) and the 15-mm nodule noted near the right common iliac artery (bottom). Advances in Radiation Oncology 2017 2, DOI: ( /j.adro ) Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

3 Figure 2 Carbon-ion radiation therapy of the 35-mm left abdominal mass. Treatment was 73.6 Gy (relative biological effectiveness) in 16 fractions. One horizontal port and 2 off-vertical ports were used, indicated by red arrows. Advances in Radiation Oncology 2017 2, DOI: ( /j.adro ) Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

4 Figure 3 (A) Pretreatment sizing of the left abdominal mass (top) and nodule in the right iliac artery region (bottom). The left abdominal mass was irradiated. (B) One month following treatment, regression is seen in both the irradiated mass (top) and nonirradiated nodule (bottom). (C) Positron emission tomography scans comparing pretreatment, 1 month posttreatment, and 13 months posttreatment, for the right iliac artery nodule. Advances in Radiation Oncology 2017 2, DOI: ( /j.adro ) Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

5 Figure 4 Computed tomography scan of the recurrence of the patient's prior colorectal cancer in a lymph node near the abdominal aorta. Advances in Radiation Oncology 2017 2, DOI: ( /j.adro ) Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

6 Figure 5 (A) Computed tomography and (B) positron emission tomography scans demonstrating before (top) and 13 months after (bottom) treatment changes. The aortic lymph node and nonirradiated 10-mm clavicular mass are both diminished. Advances in Radiation Oncology 2017 2, DOI: ( /j.adro ) Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

7 Figure 6 Two horizontal and 2 vertical ports were used for irradiation of the aortic lymph node, with 50.4 Gy (relative biological effectiveness) delivered in 12 fractions. Advances in Radiation Oncology 2017 2, DOI: ( /j.adro ) Copyright © 2017 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

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