1. Effect of activated autologous monocytes/macrophages on wound healing in a rodent model of experimental diabetes 
Xiao-yan Gu, Su-e Shen, Chong-fa Huang, Ying-na Liu, Yin-chen Chen, Ling Luo, Yanjun Zeng, Ai-ping Wang 
Diabetes Research and Clinical Practice 
Volume 102, Issue 1, Pages (October 2013)
DOI: /j.diabres
Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

2. Fig. 1
Effect of TNF-α plus IFN-γ. (A) Effect of TNF-α plus IFN-γ on the uptake of apoptotic cells by Mo/Mp in vitro. Phagocytic index of unstimualted normal Mo/Mp (a) and diabetic Mo/Mp either unstimulated (b) or stimulated with TNF-α plus IFN-γ (c). Data are mean±SD (n=8). #P<0.05 vs unstimulated normal Mo/Mp or unstimulated diabetic Mo/Mp. (B) Effect of TNF-α plus IFN-γ on the secretion of VEGF and IGF-1 by Mo/Mp. Unstimualted normal Mo/Mp (a), diabetic Mo/Mp either unstimulated (b) or stimulated with TNF-α plus IFN-γ (c) were seeded in 6-well plates. VEGF and IGF-1 levels in culture media were measured by ELISA. Data are mean±SD (n=8). *P<0.01 or #P<0.05 vs unstimulated normal Mo/Mp; **P<0.01 vs unstimulated diabetic Mo/Mp.
Diabetes Research and Clinical Practice  , 53-59DOI: ( /j.diabres )
Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

3. Fig. 2
Effect of Mo/Mp engraftment on the percentage of wound contraction at various days after wounding in rats. (A) Photomicrographs of wounds in diabetic rats 14 days after administration of the indicated Mo/Mp (1×106cells). B: Quantification of wound closure rate expressed as a percentage (%) of the initial wound size (PBS-treated normal control wound ●, PBS-treated diabetic wound ■, unstimulated diabetic Mo/Mp-treated diabetic wound ♦, or stimulated diabetic Mo/Mp-treated diabetic wound ▿). All data are mean±SD (n=6). *P<0.01 vs PBS-treated normal control wound, #P<0.05 vs PBS-treated diabetic wound.
Diabetes Research and Clinical Practice  , 53-59DOI: ( /j.diabres )
Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

4. Fig. 3
Histological assessment of wounds in diabetic rats treated with Mo/Mp on day 14. Photomicrograph of H&E-stained paraffin sections. A representative of six wounds from (A) PBS-treated normal control or (B) diabetic control and (C) unstimulated or (D) stimulated diabetic Mo/Mp-treated diabetic rats (25× magnification).
Diabetes Research and Clinical Practice  , 53-59DOI: ( /j.diabres )
Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

5. Fig. 4
Effect of Mo/Mp engraftment on VEGF expression in the wounds of rats at various days after cutaneous full-thickness wound creation. Proteins from wound were extracted and analyzed by Western blot as described in Section 2. (A) A representative of six Western blotting experiments. (B) Relative quantification of VEGF expression in the wounds. All data are mean±SD (n=6). *P<0.01 vs PBS-treated normal control; #P<0.05 vs PBS-treated diabetic wound or unstimulated diabetic Mo/Mp-treated diabetic wound.
Diabetes Research and Clinical Practice  , 53-59DOI: ( /j.diabres )
Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions