1. Heart Failure With Preserved Left Ventricular Function: Diagnostic and Therapeutic Challenges in Patients With Diastolic Heart Failure 
Michael N. Young, MD 
The American Journal of the Medical Sciences 
Volume 344, Issue 5, Pages (November 2012)
DOI: /MAJ.0b013e318246d885
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions

2. Figure 1
Electrocardiogram on hospital admission that shows sinus tachycardia, ST-T depression inferolaterally and poor R wave progression.
The American Journal of the Medical Sciences  , DOI: ( /MAJ.0b013e318246d885)
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions

3. Figure 2
Right heart catheterization 2weeks before admission yielded the hemodynamic measurements below. (A) Right atrial mean pressure was 14mmHg. (B) Right ventricular pressure was 75/15mmHg. (C) Pulmonary artery pressure was 77/35mmHg with a mean pressure of 50mmHg. (D) The mean pulmonary capillary wedge pressure was 24mmHg.
The American Journal of the Medical Sciences  , DOI: ( /MAJ.0b013e318246d885)
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions

4. Figure 3
The end-expiratory left ventricular end-diastolic pressure measured on catheterization was significantly increased at 40mmHg (arrow).
The American Journal of the Medical Sciences  , DOI: ( /MAJ.0b013e318246d885)
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions

5. Figure 4
(Top) Transmitral Doppler echocardiography shows a peak transmitral inflow velocity of 1.1 m/sec during early filling (E, white arrowhead) and 1.4 m/sec during late filling (A, boxed arrowhead) of the left ventricle. This E/A pattern is consistent with impaired ventricular relaxation. (Bottom) Tissue Doppler echocardiography reveals a mitral annular velocity of 7.0cm/sec during early filling (e’, white arrow) and 9.0cm/sec during late filling (a’, boxed arrow). Her E/e’ ratio of 15.7 and pseudonormal filling pattern based on this modality suggest a more advanced stage of diastolic dysfunction.
The American Journal of the Medical Sciences  , DOI: ( /MAJ.0b013e318246d885)
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions

6. Figure 5
Representative left atrial pressure recordings in a patient with diastolic heart failure.
The American Journal of the Medical Sciences  , DOI: ( /MAJ.0b013e318246d885)
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions

7. The American Journal of the Medical Sciences 2012 344, 399-405DOI: (10
The American Journal of the Medical Sciences  , DOI: ( /MAJ.0b013e318246d885)
Copyright © 2012 Southern Society for Clinical Investigation Terms and Conditions