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Parkinsonism & Related Disorders

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Presentation on theme: "Parkinsonism & Related Disorders"— Presentation transcript:

1 Parkinsonism & Related Disorders
Comparison of transcranial sonography-magnetic resonance fusion imaging in Wilson's and early-onset Parkinson's diseases  Jana Mašková, David Školoudík, Andrea Burgetová, Ondřej Fiala, Radan Brůha, Daniela Záhoráková, Tereza Serranová, Matěj Slovák, Olga Ulmanová, Evžen Růžička, Petr Dušek  Parkinsonism & Related Disorders  Volume 28, Pages (July 2016) DOI: /j.parkreldis Copyright © 2016 Elsevier Ltd Terms and Conditions

2 Fig. 1 Typical TCS findings in WD patient with corresponding MRI images using the fusion imaging technique. A) axial mesencephalic plane showing normal echogenicity of a substantita nigra; B) axial thalamic plane showing hyperechogenic lentiform nucleus. Numbers indicate following anatomical structures: 1 – mesencephalon; 2 – temporal lobe; 3 – cerebellum; 4 – third ventricle; 5 – frontal horn of lateral ventricle; 6 – caudate nucleus; 7 – lentiform nucleus; 8 – insula; 9 – occipital horn of lateral ventricle. Parkinsonism & Related Disorders  , 87-93DOI: ( /j.parkreldis ) Copyright © 2016 Elsevier Ltd Terms and Conditions

3 Fig. 2 Echogenicity index in A) substantia nigra (SN) and B) lentiform nucleus (NL) in control subjects, Wilson disease (WD) and early-onset Parkinson's disease (EO-PD) groups. Y-axes are differently adjusted for SN and NL values respectively. Echogenicity index in CN exhibited similar pattern as in NL and is thus not depicted in this graph. Parkinsonism & Related Disorders  , 87-93DOI: ( /j.parkreldis ) Copyright © 2016 Elsevier Ltd Terms and Conditions

4 Fig. 3 Receiver operating characteristic (ROC) of substantia nigra (SN, dashed line) and lentiform nucleus (NL, solid line) echogenicity in the differential diagnosis of Wilson's disease and early-onset Parkinson's disease. Parkinsonism & Related Disorders  , 87-93DOI: ( /j.parkreldis ) Copyright © 2016 Elsevier Ltd Terms and Conditions


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