1. Copyright © 2015 by the American Osteopathic Association.
From: Analysis of Pooled Data From Two Pivotal Controlled Trials on the Efficacy of Topiramate in the Prevention of Migraine
J Am Osteopath Assoc. 2007;107(7): doi: /jaoa
Figure Legend:
Overall study design of two pivotal North American topiramate efficacy trials. Patients who qualified for enrollment based on screening evaluations and for whom informed consent was obtained entered the prerandomization phase, which included a maximum 14-day washout period (during which any migraine-prevention medications were discontinued) and a 28-day prospective baseline period. Patients randomized to topiramate were titrated to their appropriate target dose over an 8-week titration period. Patients were maintained on topiramate (50, 100, or 200 mg/d) or placebo for 18 weeks , 14
Date of download: 10/14/2017
Copyright © 2015 by the American Osteopathic Association.
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