1. From Accelerators Physics to Nuclear Medicine
Nhât-Tân Vuong
Work Package 1: Mass separation of innovative medical isotopes

2. Marie Sklodowska-Curie
1903
Marie Sklodowska-Curie

4. Nuclear Medicine

5. Medicis-Promed

6. An Innovative Training Network
Physics
Radiochemistry
Engineering
Medicine
Biology
Strength of the network
MEDICIS-PROMED will train a new generation of entrepreneurial scientists to build an active collaboration between research institutions, private companies and hospitals in the Lemanic area and all across Europe.
A network of world leading experts offers a unique interdisciplinary background to advance the development of applications of radioisotopes in nuclear medicine and oncology.

7. The scope of the MEDICIS Project
11C based hadron therapy
Production of innovative radioisotopes
Diagnostic Imaging
Personalized Treatment of Cancer
MEDICIS = MEDical Isotopes Collected from Isolde
How are we going to do that ?
1 Prod of new isotopes
2 New radiopharmaceuticals
3 Beam technology to dev. Hadron therapy
Diagnostic imaging and therapy of cancer
Development of Radiopharmaceuticals

8. Innovative isotopes C. Muller et al. jnumed.112.107540v1
and many others…*
* CERN-MEDICIS : A New Facility. R.S. Augusto et al
C. Muller et al.
jnumed v1
Brain
213Bi-pept
Lung
177Lu-mab
Liver
166Ho
(microspheres)
Kidney
Ovary
Prostate
Leukemia
Myeloma Ac-mab
Melanoma 213Bi-mab

9. Isotope production

10. Isotope production Cyclotron. Arronax, Nantes FR
Nuclear reactor. ILL, Grenoble FR

11. CERN
1000+ isotopes of 70+ chemical elements
Nuclear Physics

12. CERN-MEDICIS: a new facility

13. From Accelerator Physics to Nuclear Medicine
CERN-Medicis Facility
Talk about chemistry

14. Production of isotopes
High energy
Protons
Target unit
spallation
fragmentation
fission
1.4 GeV protons
Example of target materials
UC2 pellets
Ta rolls

15. Nano-fibrous target material
Y-ac. nanofibers
Sanjib Showdhury - Portugal - Instituto Superior Técnico

16. Graphene coated target material
Marina Nazarova - UK - University of Manchester

17. Radioactive waste
UC2 pellets
U3O8

18. Isotope Separator On-Line (ISOL)
1.4 GeV Protons
Production of isotopes
CERN
CERN Accelerators
CERN-ISOLDE
General ISOLDE presentation
ISOL technique

19. Isotope separation Laser Production of isotopes CERN CERN Accelerators
Mass separation
Element specific
ions source
Laser
Production of isotopes
CERN
CERN Accelerators
CERN-ISOLDE
General ISOLDE presentation
ISOL technique

20. High purity laser ionization scheme
Resonance Ionization Laser Ion Source
RILIS at CERN
Vadim Gadelshin - Germany - Johannes Gutenberg-Universität Mainz

21. Chemical separation
Nhât-Tân Vuong – Switzerland - CERN

22. Transportation
Type A package
Maddalena Maietta - France - Lemer Pax

23. THANK YOU
“This research project has been supported by a Marie Skłodowska-Curie Innovative Training Network Fellowship of the European Commission’s Horizon 2020 Programme under contract number MEDICIS-PROMED”