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Common dermatology problems
Dr Ghada A. Bin Saif Assisstant professor Dermatology department King saud university & KKUH
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2 w : enlarging eruption on trunk
15 year old 2 w : enlarging eruption on trunk
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DIFFERENTIAL DIAGNOSIS
Tinea corporis (active edge) Discoid eczema (numerous, symmetrical, no central clearing) Erythema annulare centrifugum Granuloma annulare Contact allergic dermatitis Annular psoriasis Pityriasis rosea Seborrhoeic dermatitis
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Erythema annulare centrifugum
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Granuloma annulare
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Tinea corporis management ? ?
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SPECIAL STUDIES TREATMENT Scraping : KOH & fungal culture Isolated
Topical (Allylamines, imidazoles) BD X 2-4 WK Widespread Fluconazole 150 mg weekly x 2-4 w Itraconazole 200 mg OD X w Terbinafine 250 mg OD x w Grisofulvin 500 mg OD x 2-4 w
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40 year old 2 year history of knees, elbows and truncal eruption
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Plaque Psoriasis
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Plaque Psoriasis management ?
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Management of chronic plaque psoriasis
Education Arthropathy ?? Scalp : CS scalp lotion, T gel shampoo < 5 % BSA : topical -- Sequential therapy - Diprolein oint & Daivonix BD x 5d BD x 2d w PM AM w BD X 2d BD x 5d - Tazarotene - Salicylic a >10 % : phototherapy or systemic ttt
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Lichen Simplex Chronicus
55 year old 2 Y : very pruritic eruption on ankle Lichen Simplex Chronicus
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TREATMENT Stop itching + emollients
High potency topical CS +- occlusion Diprolein oint BD Dermovate oint BD IL CS Oral antihistamines ( Atarax) ?? Skin biopsy
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14 Y Old pruritic eruption in arm & legs flexors X ys worse in winter bronchial asthma intolerance to wool orbital darkening Atopic dermatitis
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28 y old lady 9 m : pruritic hand eruption bilaterally
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DIFFERENTIAL DIAGNOSIS
Contact dermatitis Tinea mannum Palmoplantar Psoriasis
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Tinea mannum
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Hand dermatitis management ? ?
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SPECIAL STUDIES TREATMENT Patch test Scraping for KOH
Avoid ppt & Emollients Potent topical CS Oral antihistamine
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30 y old gentleman 6 y : recurrent pruritic sole eruption bilaterally
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DIFFERENTIAL DIAGNOSIS
Dyshidrotic eczema Allergic contact dermatitis Tinea pedis Pustular psoriasis
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Contact dermatitis
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Tinea Pedis
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Pustular psoriasis
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Dyshidrotic eczema management ? ?
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DYSHIDROTIC ECZEMA SPECIAL STUDIES Scraping for KOH Patch test
TREATMENT Oral antihistamine Potent topical CS Botox inj Systemic therapy
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DIFFERENTIAL DIAGNOSIS (localized)
Depigmented: - Vitiligo ( acquired, pattern of depigmentation) - Piebaldism (birth, AD, site, Pig ,S, white forlock) - Chemical leucoderma Hypopigmented : - Tuberous sclerosis (birth, S , lance-ovate) - Nevus depigmentosus (birth, S, unilateral) - Post Inflammatory Hypopigmentation - Pityriasis alba (scales) - MF Nonmelanotic : - Nevus anaemicus (S)
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Tuberous sclerosis
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Nevus depigmentosus
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Nevus anaemicus
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Post Inflammatory Hypopigmentation
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Pityriasis alba
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Vitiligo management ??
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Limited Vitiligo SPECIAL STUDIES
T4, TSH, FBS, ANA/Ro/La (prior to PUVA) TREATMENT Sunscreen (sunburn, koebnerization, tanning) Class 3 topical GC OD x3w - skip a week. Monitor for SE: 2 m Topical Tacrolimus Topical PUVA Excimer laser Resistant, Stable of 2 years : Surgical
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Management ?
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25 year old gentleman 2 years: facial , upper back eruption
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DIFFERENTIAL DIAGNOSIS
Acne vulgaris ( comedons) Steroid induced acne ( monomorphic) Papulopustular Rosacea ( centrofacial, erythema, telangiectasia ) lupus miliaris disseminata faciei Perioral dermatitis Folliculitis Pseudofolliculitis barbae
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Acne Vulgaris Moderate papulopustular
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Comedonal acne
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Nodulocystic acne
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Scars
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Drug Induced Acne
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SPECIAL STUDIES When suspected ? ?
- Testosterone, prolactin, FSH/LH, DHEAS, Scan ovaries - Morning cortison, 17a-OH Progesterone Roaccutane: Preg. Test, LFT, Lipid Minocycline : ANA, LFT AT 6-8 m
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TREATMENT Mild : Topicals Comedonal : retinoids
Inflammatory: Abx, BP, azelic a Combined Moderate : Oral Abx (6-8 m) + topical keratolytic Tetracyclines (Doxycycline, minocycline) Female: Dianette + topical or oral Abx Older women: spironolactone Severe (physically, psychologically, failure to respond, scarring, GNF ): Oral isotretinoin Maintainance therapy ? ? ?
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How to use oral isotretinoin ? ?
Lab No pregnancy Dose : mg/kg/d Cumulative dose : mg/kg LFT + lipid monthly Fixed dose: 2 test normal : No more test Refresh eye drops Emollients ( lips)
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70 year old 5 year: facial flushing & eruption and eye redness No ttt use before
Papulopustular Rosacea
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Pseudofolliculitis barbae
30 year old 3 year: facial eruption, increased after shaving Pseudofolliculitis barbae
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Retinoic a Glycolic a Laser depilation
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60 year old 4 year: oily face facial and scalp eruption
Seborrhoeic Dermatitis
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TREATMENT Scalp : - shampoo ( ketoconazole, salicylic a,
selenium sulfide) - Glucocorticoids scalp lotion Face & trunk: -Low potency topical GC -Topical imidazoles (ketoconazole) Resistant: Oral ketoconazole or itraconazole (2-3w)
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25 Year old lady 1 m: localized hair loss
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DIFFERENTIAL DIAGNOSIS (acquird, localized)
Alopecia Areata Tinea capitis Trichotillomania Scarring alopecia
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Tinea capitis (Gray patch)
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Trichotillomania
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Scarring alopecia ( Lichen planopilaris)
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Alopecia areata management ? ?
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SPECIAL STUDIES CBC, TFT, antibodies, serum B12 PROGNOSTIC FACTORS - young (<5y) - Severity - Ophiasis - Duration before ttt - Nail changes
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TREATMENT Observation Intralesional CS ( TA 2.5-5 mg/ml-- /m)
Potent topical CS ( with occlusion) Anthralin , retinoic a Topical minoxidil Systemic CS PUVA
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6 Y old boy 3 weeks : localized hair fall
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DIFFERENTIAL DIAGNOSIS
Tinea capitis (kerion) Bacterial pyoderma Folliculitis decalvans Perifolliculitis capitis abscedens et suffodiens
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Tinea capitis (kerion) management ??
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SPECIAL STUDIES Hair pluck and scales: KOH & fungal culture
Wood’s lamp
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TREATMENT Education Ketoconazole shampoo Systemic antifungal
Grisofulvin (ultamicrosized 10-15mg/kg/d) 500mg PO OD X 6-8 w Itraconazole (5mg/kg/d) 200mg BD X 4-8w OR 3 pulses Terbinafine (5mg/kg/d) 250mg OD X 2-4w Fluconazole 6mg/kg/d X 3-6w Prednisolone 1 mg/kg/d X 2w
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19 year old 3 m : pruritic, short lived, recurrent eruption
Chronic urticaria
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SPECIAL STUDIES Unnecessary for acute urticaria
CBC ,Blood eosinophilia Stool examination ESR Thyroid autoantibodies
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45 y old 1 Y : finger and toe nail discoloration
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DIFFERENTIAL DIAGNOSIS
Onychomycosis Psoriasis Lichen planus Hyperthyroidism Trauma Pachyonychia congenita
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5d: Fever, joint pain, painful eruption on both chins
29 Y old lady 5d: Fever, joint pain, painful eruption on both chins Erythema Nodosum
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SPECIAL STUDIES ALL :ASO titer, throat culture, CXR, PPD TREATMENT Bed rest NSAID (Indomethacin 25mg PO TID ) KI (super sat. sol.)5 drops TID Colchicine 1mg OD Hydroxychloroquine 200mg PO BD Prednisolone
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Striae treatment ??
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