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RENAL DRUGS Henderson.

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Presentation on theme: "RENAL DRUGS Henderson."— Presentation transcript:

1 RENAL DRUGS Henderson

2 Composed of the kidneys and represents a major route to eliminate drugs.
Produces and regulates body fluid and electrolyte balance Renal System

3 A disease characterized by overproduction or insufficient elimination of uric acid within the body that will crystalize in the joints and cause pain/inflammation Gout

4 Salts which are dissolved in body fluids and are necessary in proper concentration to maintain normal body functions Ammonium Bicarbonate Calcium Chloride Magnesium Phosphate Potassium Sodium Electrolytes

5 Alter the body’s electrolyte pattern by prohibiting or enhancing excretion of electrolytes.
Uses: Hypertension (high blood pressure) CHF Fluid Retention SPECIAL NOTE: Most diuretics deplete potassium, frequently, potassium is prescribed along with a diuretic. Diuretics

6 Thiazide and related diuretics
Causes the kidney to secrete more which decreases water retention and blood pressure. Used to reduce blood pressure Side effects: Increased urination, weakness, upset stomach, dizziness Brand Generic Hydrodiuril Hydrochlorothiazide Lozol Indapamide Thiazide and related diuretics

7 Loop diuretics Very potent diuretic Used to treat CHF Brand Generic
Bumex Bumetanide Lasix Furosemide Demadex Torsemide Loop diuretics

8 Potassium Sparing diuretics
These are weak diuretics and typically are prescribed in addition to another diuretic to treat CHF. No potassium supplement required Brand Generic Aldactone Spironolactone Potassium Sparing diuretics

9 Combination diuretics
Brand Generic Moduretic Amiloride/HCTZ Maxide/Diazide Triamterene/HCTZ Aldactazide Spironolactone/HCTZ Combination diuretics

10 Pull water out of the body and into the kidneys to produce an intense diuresis in a hospital setting. Example: Mannitol Osmotic Diuretics

11 Enhance excretion of uric acid for the prevention and treatment of gout.
Side effects: Rash, kidney stones Brand Generic Zyloprim Allopurinol Benamid Probenacid Colcrys Colchicine Gout treatment


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