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Volume 18, Issue 2, Pages (March 2015)

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Presentation on theme: "Volume 18, Issue 2, Pages (March 2015)"— Presentation transcript:

1 Volume 18, Issue 2, Pages 173-179 (March 2015)
Economic Evaluation of Tocilizumab Monotherapy Compared to Adalimumab Monotherapy in the Treatment of Severe Active Rheumatoid Arthritis  Josh J. Carlson, PhD, Sarika Ogale, PhD, Fred Dejonckheere, MD, Sean D. Sullivan, PhD  Value in Health  Volume 18, Issue 2, Pages (March 2015) DOI: /j.jval Copyright © Terms and Conditions

2 Fig. 1 Use of HAQ Score in the lifetime model. The model captures changes in disease severity based on results from the HAQ, which then impacts utility, mortality rate and hospitalization rates in the model. HAQ, Health Assessment Questionnaire; QALY, quality-adjusted life year. Value in Health  , DOI: ( /j.jval ) Copyright © Terms and Conditions

3 Fig. 2 Lifetime model schematic. The schematic demonstrates how treatment influences HAQ score within the model. ACR, American College of Rheumatology; ADA, adalimumab; HAQ, Health Assessment Questionnaire; RA, rheumatoid arthritis; TCZ, tocilizumab. Value in Health  , DOI: ( /j.jval ) Copyright © Terms and Conditions

4 Fig. 3 One-way sensitivity analysis (tocilizumab monotherapy vs. adalimumab monotherapy every other week). ACR, American College of Rheumatology; HAQ, Health Assessment Questionnaire; QALY, Quality Adjusted Life Years; TNF, tumor necrosis factor. Value in Health  , DOI: ( /j.jval ) Copyright © Terms and Conditions

5 Fig. 4 Cost-effectiveness acceptability curve (tocilizumab monotherapy vs. adalimumab monotherapy every other week). The probabilistic sensitivity analyses included 2,000 simulations of 10,000 patients. ICER, incremental cost-effectiveness ratio; QALY, quality-adjusted life years. Value in Health  , DOI: ( /j.jval ) Copyright © Terms and Conditions


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