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Figure 1. Twenty-four-hour plasma ACTH concentrations in insomniacs (▪) and controls (○). The thick black line indicates the sleep recording period. The.

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Presentation on theme: "Figure 1. Twenty-four-hour plasma ACTH concentrations in insomniacs (▪) and controls (○). The thick black line indicates the sleep recording period. The."— Presentation transcript:

1 Figure 1. Twenty-four-hour plasma ACTH concentrations in insomniacs (▪) and controls (○). The thick black line indicates the sleep recording period. The error bar indicates se. *, P < 0.01. From: Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications J Clin Endocrinol Metab. 2001;86(8): doi: /jcem J Clin Endocrinol Metab | Copyright © 2001 by The Endocrine Society

2 Figure 2. Twenty-four-hour plasma cortisol concentrations in insomniacs (▪) and controls (○). The thick black line indicates the sleep recording period. The error bar indicates se. *, P < 0.01. From: Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications J Clin Endocrinol Metab. 2001;86(8): doi: /jcem J Clin Endocrinol Metab | Copyright © 2001 by The Endocrine Society

3 Figure 3. Multiple component (24 and 12 h) cosinor analysis of 24-h serum ACTH (top panel) and cortisol (bottom panel) for insomniacs (dashed line) and controls (solid line), expressed as percent variation from the mean. The thick black line on the abscissa represents the sleep recording period. *, P < 0.05. From: Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications J Clin Endocrinol Metab. 2001;86(8): doi: /jcem J Clin Endocrinol Metab | Copyright © 2001 by The Endocrine Society

4 Figure 4. Twenty-four-hour plasma cortisol concentrations in insomniacs, with low total ST (▪) vs. those with high total ST (○) (MANOVA). The thick black line indicates the sleep recording period. The error bar indicates se. *, P < 0.01. From: Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications J Clin Endocrinol Metab. 2001;86(8): doi: /jcem J Clin Endocrinol Metab | Copyright © 2001 by The Endocrine Society

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