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Precision Medicine: The Potential for Identifying Personalized Therapies for Patients with Gastro-Esophageal Cancer.

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Presentation on theme: "Precision Medicine: The Potential for Identifying Personalized Therapies for Patients with Gastro-Esophageal Cancer."— Presentation transcript:

1 Precision Medicine: The Potential for Identifying Personalized Therapies for Patients with Gastro-Esophageal Cancer

2 Disclosures

3

4

5 Epidemiology

6 Risk factors

7 Gastric Cancer: Histology

8 TN Staging of Gastric Cancer

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10 Stage and Outcomes

11 Therapy

12 First Line Metastatic Disease

13 First Line: HER2+ Disease

14 Second Line Metastatic Disease

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16 A Heterogeneous Disease

17 Four Genomic Subtypes

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20 PD-1 Inhibitors

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23 Molecular Profiling – An Example

24 Molecular Profiling – An Example

25 Molecular Profiling – An Example

26 Molecular Profiling – An Example

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28 Perthera and the Pancreatic Cancer Action Network partner on Know Your Tumor

29 Know Your Tumor Results to Date: Enrollment

30 Tissue Availability Data

31

32 Actionability: Specific Results

33 Actionable Findings in Gastric Cancer?

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37 Pitfalls and Concerns

38 Is Molecular Profiling Cost Effective?

39 Thank You


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