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Volume 188, Issue 4, Pages (October 2012)

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Presentation on theme: "Volume 188, Issue 4, Pages (October 2012)"— Presentation transcript:

1 Volume 188, Issue 4, Pages 1124-1130 (October 2012)
Effectiveness of the Combined Evaluation of KLK3 Genetics and Free-to-Total Prostate Specific Antigen Ratio for Prostate Cancer Diagnosis  Carlo-Federico Zambon, Tommaso Prayer-Galetti, Daniela Basso, Andrea Padoan, Elisa Rossi, Silvia Secco, Michela Pelloso, Paola Fogar, Filippo Navaglia, Stefania Moz, Filiberto Zattoni, Mario Plebani  The Journal of Urology  Volume 188, Issue 4, Pages (October 2012) DOI: /j.juro Copyright © 2012 American Urological Association Education and Research, Inc. Terms and Conditions

2 Figure 1 tPSA, f/tPSA and Gleason score in patients without PCa (Ref.) and those with PCa after subdivision by 3 Gleason score classes, including 6 or less, 7 and greater than 7. Columns indicate mean. Bars indicate SE. Asterisk indicates Bonferroni test for pairwise comparison p < vs reference group. The Journal of Urology  , DOI: ( /j.juro ) Copyright © 2012 American Urological Association Education and Research, Inc. Terms and Conditions

3 Figure 2 ROC curve analysis of f/tPSA in patients with different KLK3 genetics (groups 1 to 4). ROC AUC was 0.84 (95% CI 0.74–0.94) for group 1, 0.71 (95% CI 0.66–0.75) for group 2, 0.67 (95% CI 0.60–0.74) for group 3 and 0.75 (95% CI 0.68–0.82) for group 4. The Journal of Urology  , DOI: ( /j.juro ) Copyright © 2012 American Urological Association Education and Research, Inc. Terms and Conditions


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