1. Effect of the antimalarial drug halofantrine in the long QT syndrome due to a mutation of the cardiac sodium channel gene SCN5A 
Kirsi Piippo, MSc, Sam Holmström, BSc, Heikki Swan, md, Matti Viitasalo, MD, Marja Raatikka, MD, Lauri Toivonen, MD, Kimmo Kontula, md 
American Journal of Cardiology 
Volume 87, Issue 7, Pages (April 2001)
DOI: /S (00)

2. Figure 1
Pedigree of the LQT3 family. Empty circles and/or squares: unaffected women and/or men; filled circles and/or squares: affected women and/or men. Subjects marked by an arrow had halofantrine-induced torsades de pointes. Corrected QT intervals (QTc in milliseconds), when available, are shown under individual symbol. Neither clinical nor genetic data were available from those labeled with a question mark.
American Journal of Cardiology  , DOI: ( /S (00) )

3. Figure 2
Electrocardiographic recordings (paper speed 50 mm/s) of subjects I/7, II/6, II/7 and II/8. Mother (I/7) and her oldest son (II/6) had halofantrine-induced ventricular tachycardia. The younger siblings are mutation carriers but have not experienced any syncope.
American Journal of Cardiology  , DOI: ( /S (00) )