1. Volume 44, Issue 5, Pages 840-848 (May 2009)
A new tool to assess the mechanical properties of bone due to collagen degradation 
C. Wynnyckyj, S. Omelon, K. Savage, M. Damani, D. Chachra, M.D. Grynpas 
Bone 
Volume 44, Issue 5, Pages (May 2009)
DOI: /j.bone
Copyright © 2008 Elsevier Inc. Terms and Conditions

2. Fig. 1
Percent collagen weight removed versus KOH treatment time for female and male emu tibiae. Significant differences were observed in the collagen weight removed with KOH treatment time but sex was not a significant factor in collagen removal. Maximum percent collagen removed was negligible (0.05%).
Bone  , DOI: ( /j.bone )
Copyright © 2008 Elsevier Inc. Terms and Conditions

3. Fig. 2
Percent changes of bone quality measurements reported by the different measurement techniques as a function of KOH treatment time for (a) female and (b) male emu tibiae. No differences were seen between sexes. Significant (p<0.05) changes in modulus of elasticity were observed between all time points (except between 3 and 7 days), as determined by 3-point bending and MRTA for both female and male emu tibiae. DXA and QUS measurements did not detect any changes caused by KOH treatment.
Bone  , DOI: ( /j.bone )
Copyright © 2008 Elsevier Inc. Terms and Conditions

4. Fig. 3
Representative stress–strain curves for 0–14 day KOH treatment for (a) female and (b) male emu tibiae. Significant differences were seen with KOH treatment time for both sexes. There were no apparent changes in the elastic region between females and males with KOH treatment time. Significant differences were seen in the plastic region between females and males with KOH treatment time.
Bone  , DOI: ( /j.bone )
Copyright © 2008 Elsevier Inc. Terms and Conditions

5. Fig. 4
Mechanical properties as a function of KOH treatment time for female and male emu tibiae: (a) Elastic modulus: significant decrease when comparing treatment time 0-day and 14-day for both females (p<0.001) and males (p<0.001). (b) Failure stress: significant differences between sexes at all time points except the 14-day treatment. (c) Failure strain: significant increase between 0-day and 14-day KOH treatment time for males (p=0.008); significant differences between sexes at all time points. (d) Toughness: significant increase for females (p=0.018) and males (p=0.024) when comparing 0-day and 14-day KOH treatment times; significant differences between males and females at all time points except at 0-day and 14-day KOH treatment.
Bone  , DOI: ( /j.bone )
Copyright © 2008 Elsevier Inc. Terms and Conditions