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Introduction. Practical Perspectives in the Surgical Management of Parkinson Disease: LCIG.

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Presentation on theme: "Introduction. Practical Perspectives in the Surgical Management of Parkinson Disease: LCIG."— Presentation transcript:

1 Practical Perspectives in the Surgical Management of Parkinson Disease: LCIG

2 Introduction

3 LCIG: Purpose and Function

4 First Placebo-Controlled Trial of LCIG

5 LCIG Trial Extension

6 LCIG Trial Extension (cont)

7 LCIG: Long-Term Trial

8 LCIG: Long-Term Trial (cont)

9 GLORIA Efficacy

10 GLORIA Safety

11 LCIG Safety Across 4 Trials

12 Procedure-Related AEs in Patients Undergoing PEG-J

13 Non-Device AEs

14 Continuity of Care

15 Conclusions

16 Practical Perspectives in the Surgical Management of Parkinson Disease: DBS

17 Introduction

18 DBS Targets

19 Bilateral STN DBS vs Medical Management: PDQ-39

20 Bilateral STN DBS vs Medical Management: UPDRS-III

21 Bilateral STN DBS vs Medical Management: AEs

22 GPi and STN DBS vs Medical Management: Efficacy

23 GPi and STN DBS vs Medical Management: Safety

24 STN vs GPi DBS: CSP 468 at 24 Months

25 STN vs GPi DBS: CSP 468 at 24 Months (cont)

26 STN vs GPi: CSP 468 at 36 Months

27 STN vs GPi DBS

28 Long-Term Outcomes

29 DBS Systems

30 DBS Monitoring

31 Conclusions

32 Abbreviations


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