1. Blood Components

2. Tissues and Fluids 92% Blood 8%
Formed Elements 48% Plasma 55%
#1 Erythrocytes (RBC’s)
Life span 120 days
Made in Red bone marrow
2.5 million die and are replaced every second
Hematocrit indicates volume of RBC’s (normal %)
Transports gasses on HGB = 95% of proteins in a RBC, 280 million molecules of HGB/RBC
Old cells removed by liver, converted to bile, escreted in liver. Iron is recycled.
Erythropoietin = hormone that controls the production of RBC
4.2 – 6.2 million/mm3

3. Red cell dissorders Anemia Iron deficiency Hemorrhagic
Polycythemia Vera in RBC’s
Aplastic - marrow fails to produce new red blood cells
Pernicious - not enough vit. B12
Sikle cell - genetic

4. White Blood cells Leukocytes
There are five types of WBC’s.
/mm3
#1 Neutrophils – most common type 40 – 70%
Also called PMN’s – many nuclei, highly mobile, first to sight of injury
Only live about 12 hours
Granules stain neutral
Phagocytes mainly against bacteria

5. Lymphocytes 20 – 40% Second most common Make anitbodies
T-cells, B-cells
Elevated during viral infections

6. Monocytes 2-10% Largest WBC
Hang out in the tissues and become active when needed
Use blood stream for a highway to get around
Sanitary engineers
May fuse to become bigger to engulf large particles
Attract other WBC’s to injury sight

7. Eosinophils 1-6% Granuals stain red
Phagocytic cells that target foreign compounds that have reacted with antiboides
Increase dramatically during allergic reactions of parasitic infections

8. Basophils <1% Stain dark with basic dyes
Discharge histamine at sites of injury causing inflamation
Attracts other WBC’s to area

9. Leukemia – cancer
Leukocytosis – too many WBC’s
Leukopenia – Low WBC count

10. Thrombocytes platlets
5000 – 10000/mm3
Arise from megakaryocyte
Involved in blood clotting
Live 10 – 12 days

11. Plasma 55% of blood volume Enzymes, lipids, inorganic salts, vitamins
Water 92%
Protiens 7%
Albumin 33%
Globulins 38%
Fibrinogen 7%