1. Chapter 11 Introduction to Genetics
11-4: Meiosis
Objectives:
Contrast the chromosome number of body cells and gametes.
Summarize the events of meiosis.
Contrast meiosis and mitosis.

2. Introduction
Mendel’s principles of genetics require at least two things:
Each organism must inherit a single copy of every gene from each of its “parents”.
When an organism produces its own gametes, those two sets of genes must be separated from each other so that each gamete contains just one set of genes.

3. Chromosome Number Example: Consider a fruit fly, Drosophila.
A body cell in an adult fruit fly has 8 chromosomes
4 form the male parent and 4 from the female parent (Homologous – Each of the 4 chromosomes that came from the male parent has a corresponding chromosome from the female parent.)

4. Chromosome Number continued
A cell that contains both sets of homologous chromosomes is said to be diploid, which means “two sets”.
Diploid cells contains two complete sets of chromosomes.
Sometimes represented by the symbol 2N.
Example: Fruit Fly – 2N = 8
A cell that contains only a single set of chromosomes, and therefore only a single set of genes is said to be haploid, which means “one set”.
Sometimes represented by the symbol N.
Example: The gamete of a fruit fly – N = 4

5. Phases of Meiosis
Meiosis is a process of reduction division in which the number of chromosomes per cell is cut in half through the separation of homologous chromosomes in a diploid cell.
Meiosis usually involves two distinct divisions, called meiosis I and meiosis II.
By the end of meiosis II, the diploid cell that entered meiosis has become 4 haploid cells.

6. Meiosis I

7. Crossing-Over
During prophase I, the homologous chromosomes exchange portions of their chromatids in a process called crossing-over.
Crossing over results in the exchange of alleles between homologous chromosomes and produces new combinations of alleles.

8. Something’s Different
Neither of the daughter cells has the two complete sets of chromosomes that it would have in a diploid cell.
The two cells produced by meiosis I have sets of chromosomes and alleles that are different from each other and from the diploid cell that entered meiosis I.

9. Meiosis II
The two cells produced by meiosis I that enter meiosis II, do not go through a round of chromosome replication before entering meiosis II.

10. Gamete Formation Male
In male animals, the haploid gametes produced by meiosis are called sperm.
In some plants, pollen grains contain haploid sperm cells.

11. Gamete Formation Female
In many female animals, the
cell divisions at the end of
meiosis I and meiosis II are
uneven, so that a single cell,
which becomes an egg,
receives most of the
cytoplasm.
The other three cells produced
in the female during meiosis
are known as polar bodies
and usually do not participate
in reproduction.

12. Comparing Mitosis and Meiosis
Mitosis results in the production of two genetically identical diploid cells, whereas meiosis produces four genetically different haploid cells.
Mitosis
Meiosis
Begins with
A diploid cell
Produces
2 identical diploid daughter cells
4 genetically different haploid cells
Purpose
Allows an organism’s body to grow and replace cells
How sexually reproducing organisms produce gametes

13. 11-4 Section Assessment Describe the main results of meiosis.
What are the principal difference between mitosis and meiosis?
What do the terms diploid and haploid mean?
What is crossing over?