1. Additional Chapter 6 information
Gas Exchange Data
03/07/2011

2. Gas Exchange and Ventilatory Responses – pg.144
VO2max or VO2peak (difference?) is necessary and is “a powerful marker of prognosis”.
Study: patients with <4.9 METS (17.2 ml/kg/min)had the highest rate of cardiovascular disease and all cause mortatlity as compared to those with higher METS of ( ).
For every one MET increase in exercise capacity there is a 12% improvement in survival.

3. RR = rest 12-15 bpm Ex: 40-50 bpm RER VE VCO2
>60 bpm = hyperventilation
RER VE
VCO2

4. RQ, RER, R: Gas exchange - measured at the mouth not the tissue level.
RER or R = VCO2 production
VO2 consumption
Composition of atmospheric air and expired air in a typical subject. Note that only a fraction of the oxygen inhaled is taken up by the lungs.
Component
Atmospheric Air (%)
Expired Air (%) O2
20.85
15.3
CO2
0.03
3.6
75% of O2 consumed is converted to CO2, so what will happen to R during Exercise?

5. Respiratory Exchange Ratio
RER: Tells what type of fuel we are burning - Fats, CHO, combination of both.
RER = 0.7 predominately fats as a fuel
R = 0.85 – 50% CHO and 50% Fats
RER = % CHO as a fuel, recent ingestion of CHO. [1,2]

6. RQ R = 0.7 - 0.95 Normal Resting Value [2]
R = at max then rises to >1.4 or 1.5 during recovery. R will increase dramatically during recovery as the body tries to eliminate CO2 stores [2]

7. VE: Represents the volume of air inspired by the lungs in one minute.
Ventilation (VE) (L/min) = RR (br/min) x tidal volume (L)
For rest conditions,
VE (L/min) = 12 (br/min) x 0.5 (L) = 6 L/min
For exercise at VO2max,
VE (L/min) = 60 (br/min) x 3.0 (L) = 180 L/min