1. Umm Al-Qura University
بسم الله الرحمن الرحيم
Umm Al-Qura University
Health Sciences College at Al-Leith
Department of Public Health
Lecture (5)

2. Leishmania parasites

3. Objectives 1/ Know of Leishmania parasites classification
and Geographical distribution.
2/ Study of Leishmania parasites External Morphology, Habitat, Life cycle, Mode of Transmission, Pathogenicity.
3/ Show Symptoms of Leishmaniasis disease.
4/ Show Laboratory diagnosis of Leishmania parasites .
5/ Know Treatment and prevention.

4. Leishmaniasis
The Leishmaniases are diseases caused by protozoan parasites from more than 20 Leishmania species that are transmitted to humans by the bites of infected female phlebotomine sandflies.

5. Sand fly

6. داء الليشمانيا Leishmaniasis) )

7. Leishmaniasis
The Leishmaniases are diseases caused by protozoan parasites from more than 20 Leishmania species that are transmitted to humans by the bites of infected female phlebotomine sandflies.

8. 8

9. 9

10. 10

11. There are three main forms of the disease:
1- cutaneous leishmaniasis,
2- visceral leishmaniasis or kala-azar, and
3- mucocutaneous leishmaniasis.

12. 1- Visceral
Estimated cases of visceral leishmaniasis (VL) and over deaths annually
2- Cutaneous
1 millionCases of cutaneous leishmaniasis (CL) reported in the last 5 years.
3- At risk
310 millionPeople at risk of infection in six countries reporting over 90% VL cases worldwide.

13. Burden and distribution cutaneous Leishmaniasis have affected different parts Afghanistan and the Syrian Arab Republic.
visceral Leishmaniasis in East Africa (Ethiopia, Kenya, South Sudan and Sudan) have caused high morbidity and mortality in affected communities.

20. الطفيل في الانسان

22. Cutaneous Leishmaniasis:

24. Mucocutaneous Leishmaniasis

26. Visceral Leishmaniasis:

27. Symptoms Symptoms of cutaneous leishmaniasis: Breathing difficulty.
Skin sores.
Stuffy nose, runny nose, and nosebleeds
Swallowing difficulty
Ulcers in the mouth, tongue, gums, lips, nose, and inner nose

28. Symptoms visceral infection in children:
Cough.
Diarrhea.
Fever.
Vomiting.
Abdominal discomfort.
Night sweats
Scaly, gray, dark, ashen skin
Thinning hair
Weight loss

29. Diagnosis

30. Treatment Meglumine antimoniate Sodium stibogluconate
Other drugs that may be used include:
Amphotericin B
Ketoconazole
Miltefosine
Paromomycin
Pentamidine

31. Prevention and control
Prevention and control of leishmaniasis requires a combination of intervention strategies because transmission occurs in a complex biological system involving the human host, parasite, sandfly vector and in some causes an animal reservoir host. Key strategies for prevention are listed below:
1-Early diagnosis and effective case management.
2- Vector control.
3- Effective disease surveillance.
4- Control of animal reservoir hosts.
5- Social mobilization and strengthening partnerships.

32. Bednet protection from sand flies
Vector Control
Bednet protection from sand flies 32

33. Thanks
Radia 33