1. Precision Dermatology Company Profile
Dec 2013
117 East 55th Street, New York, NY | (212)

2. Company Overview PreCision Dermatology Company Overview
General Information
Corporate Headquarters:
900 Highland Corporate Drive Cumberland, RI Phone: (888)
Ownership: Private
New York Office:
129 West 29th Street, Suite 400
New York, NY 10001
Phone: (646)
Fax: (646)
Company Overview
PreCision Dermatology is focused on building a portfolio of innovative products which provide therapeutic solutions to a wide variety of skin conditions.
The company is divided into two divisions:
Onset Dermatologics, which markets prescriptions products to treat various skin diseases
PrecisionMD, which offers skin care solutions for UV or aging related skin deterioration
Current Product Portfolio (only including product with sales on IMS as of Aug 2013):
PreCision’s prescription products are formulated using its proprietary DELEVO® Foam Technology, a unique drug delivery platform that provides 1) higher levels of proven active ingredients to the skin with fewer side effects; and 2) sustained skin hydration which enhances the overall patient experience.
Current disease targets include skin barrier restoration, dermatoses, rosacea, acne, seborrheic dermatitis, and scaling associated with hyperkeratotic skin.
Management
Officer
Position
Robert Moccia
COO, Pres. (Onset)
Steven Tannenbaum
EVP, CFO
Rick Havens
SVP, S&M (Onset)
Martin Redmon
SVP, R&D and TO
Board of Directors
Member
Affiliation(s)
Juliet Bakker
Longitude Capital
Garen Bohlin
Constellation
William Crouse
HealthCare Venture
Michael Heffernan
Collegium
Patrick Heron
Frazier Healthcare
Robert Jevon
Boston Millennia
Adele Oliva
Quaker Partners
William Robb
NovaQuest Capital
Immanuel Thangaraj
Essex Woodlands
Source: Company website and IMS.

3. Onset Dermatologics Prescription Products – Acquired From Triax
Recent News
May ‘13 – Onset Dermatologics announced the availability of Aurstat® Anti-Itch Hydrogel. Aurstat® is a treatment for itch, including itch related to atopic dermatitis. Atopic dermatitis is also called eczema. Aurstat® contains HOCl (hypochlorous acid) as a preservative.
Jan ‘13 – PrecisionMD, the developer of innovative therapeutic and cosmetic skincare solutions, reveals the impressive results of a new study showing that its Vivatia Brightening Complex containing two percent hydroquinone (HQ), is as effective for reducing skin pigmentation as a four percent HQ formulation. For consumers this means fast, dramatic results at a lower percentage of hydroquinone.
Dec ‘12 – Announced the Fall 2012 launch of DermaChromatic, the only product that uses a patent-pending copper-chlorophyllin anti-redness technology to visibly improve skin redness in as little as two weeks.
Apr ‘12 – Announced the acquisition of the assets of Triax Pharmaceuticals.  Triax markets a range of branded prescription dermatology products, including a leading mid-potency topical steroid, Locoid®, and the acne treatments Minocin® and Tretin X™.
Portfolio Overview
In April 2012, PreCision acquired three group of assets from Triax Pharmaceuticals to expand its offering of high quality branded dermatological products. These assets include:
Product
Description
2012 Gross Sales ($m)
LTM Gross Sales ($m)
Locoid Suite
Indications: 1) relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses in adults and; 2) topical treatment of mild to moderate atopic dermatitis in patients 3 months of age and older
Hydrocortisone butyrate 0.1%
Patent protection through 2014 for cream and 2025 for lotion
$43.9
$50.6
Tretin-X
Indication: Topical application in the treatment of acne vulgaris
Tretinoin cream %
No generic substitution in the cream form
3.6
5.8
Minocin
Indication: pellet-filled capsules used as adjunctive therapy for severe acne
Minocycline HCl
Available in 50mg and 100mg strengths
No generic substitution in oral form
3.7
Total
$51.1
$60.1
Notes: LTM through August 2013
Together, these products account for about 60% of the LTM gross sales through August 2013.
Source: Company website and IMS.

4. Company Overview PreCision Dermatology Company Overview
General Information
Corporate Headquarters:
900 Highland Corporate Drive Cumberland, RI Phone: (888)
Ownership: Private
New York Office:
129 West 29th Street, Suite 400
New York, NY 10001
Phone: (646)
Fax: (646)
Company Overview
PreCision Dermatology is focused on building a portfolio of innovative products which provide therapeutic solutions to a wide variety of skin conditions.
The company is divided into two divisions:
Onset Dermatologics, which markets prescriptions products to treat various skin diseases
PrecisionMD, which offers skin care solutions for UV or aging related skin deterioration
Current Product Portfolio (only including product with sales on IMS as of Aug 2013):
PreCision’s prescription products are formulated using its proprietary DELEVO® Foam Technology, a unique drug delivery platform that provides 1) higher levels of proven active ingredients to the skin with fewer side effects; and 2) sustained skin hydration which enhances the overall patient experience.
Current disease targets include skin barrier restoration, dermatoses, rosacea, acne, seborrheic dermatitis, and scaling associated with hyperkeratotic skin.
Management
Officer
Position
Robert Moccia
COO, Pres. (Onset)
Steven Tannenbaum
EVP, CFO
Rick Havens
SVP, S&M (Onset)
Martin Redmon
SVP, R&D and TO
Board of Directors
Member
Affiliation(s)
Juliet Bakker
Longitude Capital
Garen Bohlin
Constellation
William Crouse
HealthCare Venture
Michael Heffernan
Collegium
Patrick Heron
Frazier Healthcare
Robert Jevon
Boston Millennia
Adele Oliva
Quaker Partners
William Robb
NovaQuest Capital
Immanuel Thangaraj
Essex Woodlands
Source: Company website and IMS.

5. Prescription Products – Acquired From Triax
Recent News
May ‘13 – Onset Dermatologics announced the availability of Aurstat® Anti-Itch Hydrogel. Aurstat® is a treatment for itch, including itch related to atopic dermatitis. Atopic dermatitis is also called eczema. Aurstat® contains HOCl (hypochlorous acid) as a preservative.
Jan ‘13 – PrecisionMD, the developer of innovative therapeutic and cosmetic skincare solutions, reveals the impressive results of a new study showing that its Vivatia Brightening Complex containing two percent hydroquinone (HQ), is as effective for reducing skin pigmentation as a four percent HQ formulation. For consumers this means fast, dramatic results at a lower percentage of hydroquinone.
Dec ‘12 – Announced the Fall 2012 launch of DermaChromatic, the only product that uses a patent-pending copper-chlorophyllin anti-redness technology to visibly improve skin redness in as little as two weeks.
Apr ‘12 – Announced the acquisition of the assets of Triax Pharmaceuticals.  Triax markets a range of branded prescription dermatology products, including a leading mid-potency topical steroid, Locoid®, and the acne treatments Minocin® and Tretin X™.
Portfolio Overview
In April 2012, PreCision acquired three group of assets from Triax Pharmaceuticals to expand its offering of high quality branded dermatological products. These assets include:
Product
Description
2012 Gross Sales ($m)
LTM Gross Sales ($m)
Locoid Suite
Indications: 1) relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses in adults and; 2) topical treatment of mild to moderate atopic dermatitis in patients 3 months of age and older
Hydrocortisone butyrate 0.1%
Patent protection through 2014 for cream and 2025 for lotion
$43.9
$50.6
Tretin-X
Indication: Topical application in the treatment of acne vulgaris
Tretinoin cream %
No generic substitution in the cream form
3.6
5.8
Minocin
Indication: pellet-filled capsules used as adjunctive therapy for severe acne
Minocycline HCl
Available in 50mg and 100mg strengths
No generic substitution in oral form
3.7
Total
$51.1
$60.1
Notes: LTM through August 2013
Together, these products account for about 60% of the LTM gross sales through August 2013.
Source: Company website and IMS.

6. Prescription Products – Internally Developed Using DELEVO
Onset Dermatologics
Hylatopic Plus (Cream & Foam)
Indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis
Also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process
No. 1 prescribed skin barrier repair therapy brand
Hylatopic Plus – Aurstat Kit
Combination therapy with the convenience of a single prescription and copay
Aurstat™ Skin & Wound Hydrogel is indicated for the relief of itch and pain from minor skin irritations, lacerations, abrasions and minor burns
BenzEFoam suite
5.3% benzoyl peroxide
Indicated for use in the topical treatment of mild to severe acne vulgaris
Clarifoam EF
Sodium Sulfacetamide 10%, Sulfur 5% Emollient Foam
Indicated in the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis
Combines proven APIs with a delivery method that facilitates patient compliance
Kerafoam / Kerafoam 42
Indicated for softening, smoothing and removing rough scaling hyperkeratotic skin in conditions such as xerosis, ichthyosis, skin cracks and fissures, dermatitis, eczema, psoriasis, keratoses and calluses.
Hylatopic suite and Aurstat suite
Combined LTM Gross Sales: $20.1M
Benzefoam and Benzefoam Plus
Combined LTM Gross Sales: $15.5M
Clarifoam EF and Keraform
Combined LTM Gross Sales: $3.0M
These products account for the remaining 40% of the LTM gross sales through Aug 2013
Source: Company website and IMS.

7. PrecisionMD PrecisionMD: Skin Care Products
Precision’s Skin Care Product Line Focuses on 5 Skin Conditions
Sun Damage – Celfix DNA suite
Using Celzyme Technology, an exclusive PrecisionMD blend of three essential enzymes that help reduce the visible signs of aging caused by damage from the sun:
Photolyase
Endonuclease
OGG1
Pigmentation – Dermaceutic treatment system
Combines a unique mix of skin rejuvenation and brightening ingredients to deliver visible results without the use of harsh chemicals often found in other products on the market
Used in Europe for over 10 years and is the No.1 peel system in France
Comes in 3 different configurations and strengths based on skin condition and patient needs
Redness – DermaChromatic suite
The only product that uses a patent-pending nanosomal delivery system for copper-chlorophyllin complex called Phytochromatic CHLCu™, which is loaded into liposomes designed for controlled release of the ingredients
Clinical proof vs. baseline:
100% had improvement at 2 weeks
Visible redness reduced, on average, by 54% at week 2 and by 68% at week 4
Statistically significant (p<0.05) reduction in oiliness and appearance of pore size in 3 weeks
Source: Company website.

8. PrecisionMD PrecisionMD: Skin Care Products
Precision’s Skin Care Product Line Focuses on 5 Skin Conditions
Loss of Firmness – Relastin suite
The only product that uses patent-pending Zinc Firming Complex to visibly improve skin firmness and elasticity
Compared to benchmark (a leading copper peptide eye product):
A randomized double-blinded study showed a 37% decrease in coarse wrinkles, 29% decrease in fine lines and wrinkles, 30% decrease in infraorbital puffiness and 43% decrease in infraorbital laxity
Aging – Vivatia suite
Uses a proprietary foam delivery system that was previously only available by presciption to deliver higher, more effective levels of anti-aging ingredients gently to the skin
Faster Snap Time vs. Benchmark
Significant Aesthetic Improvement at Week 4
Source: Company website.