1. Date of download: 9/19/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Patient enrollment flowchart. IN-MMAD indicates Intranasal-Midazolam Mucosal Atomization Device; RD, rectal diazepam. Figure Legend:

2. Date of download: 9/19/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Time from medication use to seizure cessation (difference, 1.3 minutes; 95% confidence interval, 0.0-3.5; P =.09). Confidence intervals and P values were calculated using Wilcoxon rank sum tests and Mann-Whitney U tests. IN-MMAD indicates Intranasal- Midazolam Mucosal Atomization Device; RD, rectal diazepam. Figure Legend:

3. Date of download: 9/19/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Witnessed total seizure time (difference, 2.0 minutes; 95% confidence interval, 1.0-5.7; P =.25). Confidence intervals and P values were calculated using Wilcoxon rank sum tests and Mann-Whitney Utests. IN-MMAD indicates Intranasal-Midazolam Mucosal Atomization Device; RD, rectal diazepam. Figure Legend:

4. Date of download: 9/19/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Witnessed time to medication administration (difference, 0.0 minutes; 95% confidence interval, −1.0 to 1.0; P =.57). Confidence intervals and P values were calculated using Wilcoxon rank sum tests and Mann-Whitney U tests. IN-MMAD indicates Intranasal- Midazolam Mucosal Atomization Device; RD, rectal diazepam. Figure Legend: