1. Date of download: 9/18/2016 From: Behavioral Programs for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis Ann Intern Med. 2015;163(11):848-860. doi:10.7326/M15-1400 Summary of evidence search and selection. T1DM = type 1 diabetes mellitus; T2DM = type 2 diabetes mellitus. * One study was included for both T1DM and T2DM. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2. Date of download: 9/18/2016 From: Behavioral Programs for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis Ann Intern Med. 2015;163(11):848-860. doi:10.7326/M15-1400 Rank order of relative effectiveness for HbA 1c of behavioral programs and active comparators versus usual care. Results of a network meta-analysis incorporating direct and indirect comparisons for the outcome of HbA 1c are shown, with nodes for program components and delivery factors. All arms in each study were categorized and then grouped into “nodes” of similar arms. Arms defined as behavioral programs were grouped on the basis of their components and delivery factors. All nodes were then compared with the usual care node, using direct and indirect evidence while maintaining the randomization within each individual study. Each node of behavioral programs differs from the others by only 1 level in a category of program component, intensity, mode of communication, delivery method, and (for DSME programs only) delivery personnel. The dots and horizontal lines represent the mean difference and 95% credible interval for the nodes relative to usual care. Our predetermined threshold for clinical importance was a reduction in HbA 1c of 0.4% or greater. Values for the mean differences and 95% credible intervals are included in Appendix Table 6. DSME = diabetes self- management education; HbA 1c = hemoglobin A 1c ; HCP = health care professional. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3. Date of download: 9/18/2016 From: Behavioral Programs for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis Ann Intern Med. 2015;163(11):848-860. doi:10.7326/M15-1400 Network diagram for hemoglobin A 1c. Each node in the network is depicted; the lines show the comparisons that contributed to the analysis. The largest circle indicates the usual care node, with which all other nodes were compared directly or indirectly. The numbering of the nodes reflects the rank order of their effectiveness in reducing hemoglobin A 1c relative to usual care; for definitions of the program components and delivery factors that correspond to each rank number, see Figure 2. The number of studies and sample size are provided. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

4. Date of download: 9/18/2016 From: Behavioral Programs for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis Ann Intern Med. 2015;163(11):848-860. doi:10.7326/M15-1400 Rank order of relative effectiveness for BMI of behavioral programs and active comparators versus usual care. Results of a network meta-analysis for BMI are shown, with nodes of programs characterized by program components and delivery factors. Usual care is the reference comparison. Each group differs by at least 1 level in the categories of program component, intensity, mode of communication, and delivery method. The dots and horizontal lines represent the mean difference and 95% credible intervals relative to usual care. Values for the mean differences and 95% credible intervals are included in Appendix Table 7. BMI = body mass index; DSME = diabetes self-management education. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians