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Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated.

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Presentation on theme: "Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated."— Presentation transcript:

1 Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin: Potential for False- Positive Diagnoses of Type 2 Diabetes Using New Diagnostic Criteria JAMA. 1999;281(13):1203-1210. doi:10.1001/jama.281.13.1203 The third National Health and Nutrition Examination Survey (NHANESIII) data set had 2836 subjects and the Meta-Analysis Research Groupdata set had 8917. To convert hemoglobin A1c frompercentage of total hemoglobin to proportion of total hemoglobin,multiply by 0.01. See Table 1 for percentage of subjects in each strataof fasting plasma glucose concentrations and "Methods" fordescription of study population and for determination of upper limitsof normal of hemoglobin A1c levels. Figure Legend:

2 Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin: Potential for False- Positive Diagnoses of Type 2 Diabetes Using New Diagnostic Criteria JAMA. 1999;281(13):1203-1210. doi:10.1001/jama.281.13.1203 Diagnosis based on fasting plasma glucose concentrations of 7.0 to7.7 mmol/L (126-139 mg/dL) and 2-hour glucose concentrations of lessthan 11.1 mmol/L (200 mg/dL) and by the old criteria (the cohort ofpatients diagnosed as having diabetes mellitus by 2-hour glucoseconcentrations of 11.1 mmol/L (200 mg/dL) or higher but with FPGconcentrations <7.0 mmol/L [126 mg/dL]). To convert hemoglobinA1c from percentage of total hemoglobin to proportion oftotal hemoglobin, multiply by 0.01. Figure Legend:

3 Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin: Potential for False- Positive Diagnoses of Type 2 Diabetes Using New Diagnostic Criteria JAMA. 1999;281(13):1203-1210. doi:10.1001/jama.281.13.1203 To convert hemoglobin A1c from percentage of totalhemoglobin to proportion of total hemoglobin, multiply by 0.01. Toconvert glucose from milligrams per deciliter to millimoles per liter,multiply by 0.05551. Data adapted from McCance etal. Figure Legend:

4 Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin: Potential for False- Positive Diagnoses of Type 2 Diabetes Using New Diagnostic Criteria JAMA. 1999;281(13):1203-1210. doi:10.1001/jama.281.13.1203 To convert hemoglobin A1c from percentage of totalhemoglobin to proportion of total hemoglobin, multiply by 0.01. Toconvert glucose from milligrams per deciliter to millimoles per liter,multiply by 0.05551. Data adapted from Engelgau etal. Figure Legend:

5 Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin: Potential for False- Positive Diagnoses of Type 2 Diabetes Using New Diagnostic Criteria JAMA. 1999;281(13):1203-1210. doi:10.1001/jama.281.13.1203 Taken from unpublished data on 40- to 74-year-old participants(Katherine Flegal, PhD, written communication, July 1997). To converthemoglobin A1c from percentage of total hemoglobin toproportion of total hemoglobin, multiply by 0.01. To convert glucosefrom milligrams per deciliter to millimoles per liter, multiply by0.05551. Figure Legend:

6 Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin: Potential for False- Positive Diagnoses of Type 2 Diabetes Using New Diagnostic Criteria JAMA. 1999;281(13):1203-1210. doi:10.1001/jama.281.13.1203


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