1. Cortical Plasticity Representational plasticity - induction - mechanisms Hyperacuity - intramodal effects - intermodal effects Clinical relevance Cross-modal plasticity

2. Representational plasticity

3. Amputation, deafferentation

4. - after 2 years Effect of amputation on the cortical representation in SI

5. Deafferentation of the glabrous part of D1 and D2 by nerve transection dorsal, hairy silent Area 3b

6. Reorganization of the thalamic representation

7. Deafferentation of the cortical representation by thalamic lesion

8. Experience dependent plasticity Training and learning

9. Extensive multidigit stimulation

10. Reversibility and dynamics

11. Return of esthesia Effect of anesthesia on the size of the RF of an SI neuron

12. Effect of amputaion on the RF size in SI

13. Mechanisms

14. Convergence, divergence

15. Relationship of intrinsic cortical connections and peripheral innervation

16. Divergence in the major somatosensory pathway

17. A possible role for the thalamocortical circuitry in regulating cortical plasticity

18. Microstructure of the somatosensory RF

19. Unmasking A role for lateral inhibition

20. Effect of disruption of local inhibition on the RF size in SI

21. Forward masking increases lateral inhibition

22. Rapid unmasking by decreasing tonic inhibition

23. Synaptic plasticity LTP/LTD

24. Upper layer horizontal connections play pivotal role in representational plasticity

25. Hyperacuity

26. Intramodal effects Amputation, reversible inactivation

27. Sensitivity differences between fingers in normal cases

28. AMPUTATION Increased representation, better performance?

29. Reversible inactivation: callosal interactions Behavior

30. Reversible inactivation: callosal interactions Brain activation (EEG)

31. Map reorganization Clinical relevance

32. Phantom feelings, Phantom pain

33. Focal hand dystonia:Writer’s-, Musician’s Cramp

34. Aberrant, increased plasticity

35. Neuronal basis of map reorganization: unresolved issues

36. Cross-modal plasticity Blindness

37. Intermodal effects

38. Blindness induced somatosensory changes

39. Increased tactile sensitivity

40. Cross-modal effects

41. Axonal rerouting

42. Tactile functions of the visual cortex

43. Rewiring Subcortical pathways

44. Uni- and heteromodal connections Cortical pathways

45. Speech processing in the visual cortex