1. Renub Research www.renub.com High Intensity Focused Ultrasound – Product Analysis Renub Research www.renub.com Published: September, 2015 Copyright © 2015 Renub Research – All Rights Reserved

2. Renub Research www.renub.com Table of Contents 1.Executive Summary 2.Worldwide – High Intensity Focus Ultrasound (HIFU) Manufacturers 2.1Region wise – High Intensity Focus Ultrasound (HIFU) Research Sites 2.2Region wise – Technical Research Sites 2.3Region wise – Pre–Clinical Research Sites 2.4Region wise – Clinical Research Sites

3. Renub Research www.renub.com Continue (www.renub.com) 3.EDAP TMS 3.1EDAP TMS – HIFU Division Business Overview 3.2EDAP TMS – HIFU Division Business Strategy 3.3EDAP TMS – HIFU Products 3.4EDAP TMS – HIFU Division Patents and Intellectual Property

4. Renub Research www.renub.com Continue (www.renub.com) 3.5EDAP TMS – HIFU Division Clinical & Regulatory Status 3.5.1Clinical & Regulatory Status in Europe 3.5.2Clinical & Regulatory Status in the United States 3.5.3Clinical & Regulatory Status in Japan 3.5.4Clinical & Regulatory Status in China

5. Renub Research www.renub.com Continue (www.renub.com) 3.6 EDAP TMS – HIFU Clinical Data 3.7 EDAP TMS – HIFU Division Revenue & Market Potential 3.7.1 Market Potential 3.7.2 EDAP TMS – HIFU Revenue 3.8 EDAP TMS – Latest Development in High Intensity Focus Ultrasound (HIFU) 3.8.1Year 2015 3.8.2Year 2014 3.8.3Year 2013

6. Renub Research www.renub.com Continue (www.renub.com) 4.Sonacare Medical 4.1SonaCare Medical – HIFU Products 4.1.1Sonablate 500 4.1.2Sonatherm 4.1.3Sonablate 500 & Sonatherm Regulatory Status 4.2SonaCare Medical – Latest Development in High Intensity Focus Ultrasound (HIFU)

7. Renub Research www.renub.com Continue (www.renub.com) 5.Haifu 5.1Haifu 5.1.1Haifu – HIFU Products 5.2Haifu – HIFU Clinical Center 5.3Patients Treated with Haifu HIFU devices in Different Hospitals 5.3.1China – Suining Central Hospital 5.3.2South Korea – St. Peter’s Hospital

8. Renub Research www.renub.com Continue (www.renub.com) 6. Insightec 6.1HIFU Products 6.1.2Insightec – Treatment Centers 6.2Insightec – Revenue & Forecast 6.3Insightec – Latest Development in Hig Intensity Focus Ultrasound (HIFU) 7.Theraclion 7.1Theraclion – HIFU Products 7.2Theraclion – Latest Development in High Intensity Focus Ultrasound (HIFU) 7.3Theraclion – HIFU Revenue

9. Renub Research www.renub.com Continue (www.renub.com) 8.Alpinion 8.1Philosophy 8.2Alpinion – HIFU Products 8.2.1Alpius 900 8.2.2VIFU 2000 8.3Alpinion – HIFU Revenue 9.Shanghai A&S Co., LTD 9.1Shanghai A&S Co., LTD – HIFU Products 9.1.1HIFUNIT–9000 Ultrasound Ablation System

10. Renub Research www.renub.com Continue (www.renub.com) 10.Mianyang Sonic Electronic Ltd. 10.1Mianyang Sonic Electronic Ltd. – HIFU Products 10.1.1 CZ901 type high intensity focused ultrasound tumor therapeutic system

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