1. Copyright © 2006 by Elsevier, Inc. Muscle Metabolic Systems Figure 84-1; Guyton & Hall

2. Copyright © 2006 by Elsevier, Inc. Muscle Metabolic Systems phosphate –enough stored for 8-10 sec max work –can supply 4x ATP/min as aerobic glycolysis –anaerobic –strongly inhibited by low pH –forms lactic acid –can supply 2.5x ATP/min as aerobic

3. Copyright © 2006 by Elsevier, Inc. Muscle Metabolic Systems aerobic can last indefinitely metabolic recovery –lactic acid-->glucose-->glycogen –oxygen debt restoration depends on carbohydrate in diet –requires 48 hr

4. Copyright © 2006 by Elsevier, Inc. Oxygen Debt

5. Copyright © 2006 by Elsevier, Inc. Restoration of Glycogen is Dependent on Diet Figure 84-3; Guyton & Hall

6. Copyright © 2006 by Elsevier, Inc. Muscle Endurance –largely a function of glycogen stores in muscle cells and liver –dependent on diet endurance (min) glycogen(g/Kg) –hi carb diet24040 –mixed diet12020 –hi fat diet 85 6

7. Copyright © 2006 by Elsevier, Inc. Endurance is Dependent on Diet Figure 84-4; Guyton & Hall