1. Tissues

2. Stem Cells The initial fertilized human cell (zygote) is a totipotent stem cell – Can turn into any cell in the human body – A stem cell is immortal and continues to undergo mitosis

3. Adult cells Most tissues in the body are made of adult (amitotic) cells – A layer of stem cells remains to replenish these cells – These stem cells are NOT totipotent but are still stem cells (e.g. base of skin) These adult cells are arranged into tissues – Group of similar specialized cells that work together

4. Human Tissues There are four classifications of human tissues Epithelial tissue Connective tissue Muscle tissue Nervous tissue

5. Tissue Functions Epithelial: Form boundaries between different environments and secrete things Connective: Support, protect and transport Muscle: Contracts (produces force) Nervous: Transmits electrical impulses

6. Electrical Activity Muscle tissue and Nervous tissue are electrically active – Use ion pumps to create electrical voltage – Use voltage to send signals quickly over long distances Electrically active tissue responds to electrical currents

7. Epithelial Tissue Epithelial tissues all form boundaries between different environments – Wrapped around most organs – Form exterior of skin and interior of blood vessels, digestive/urinary tracts, etc – Glandular tissue secretes substances into these environments

8. Epithelial Tissue Types Different epithelial tissues have different structures – The function of any tissue is determined by its structure Epithelial cells may be squamous (flat), columnar (tall) or cuboidal (not too flat or tall) Epithelial tissue may be simple (one layer) or stratified (many layers)

10. Glandular Tissue A gland is any epithelial tissue that releases a substance that leaves the tissue – Sweat/Mucus/Saliva – Signal molecules (hormones) Any secretion that stays in the bloodstream is called endocrine Any secretion that leaves the bloodstream is called exocrine

11. What about Digestive Juices? Endocrine tissue releases chemicals into the bloodstream The digestive tract is technically outside the body – Digestive secretions are from exocrine glands

12. Connective Tissue Connective tissues are the broadest category of tissues – Support, protect, and transport Fibrous connective tissues serve various protective and structural purposes – Composed primarily of fibroblasts which build the fibers that hold the tissue together There are also four “special” connective tissues – You have already heard of these!

14. Muscle Tissue All muscle tissue is stimulated by electrical signals – Some muscle tissue is voluntary (stimulated by nerves coming from the conscious brain) – Other muscle tissue is involuntary (stimulated either by the unconscious brain or automatically)

15. Muscle Tissue Types Skeletal Muscle – Voluntary – Attached to bones Cardiac Muscle – Heart muscle – Involuntary – Autorhythmic Smooth Muscle – Involuntary – Wrapped around hollow organs such as stomach

16. Nervous Tissue Nervous tissue consists of two types of cells: – Neurons: electrically active signal cells – Glial cells or neuroglia: Support cells that protect neurons

17. Brain Tissue

18. Organs An organ is made of two or more tissues – Almost all have one or more connective tissue layers around the outside An organ serves a specific overall function to regulate homeostasis in some way An organ works with other organs in an organ system

19. Next week: Monday: Our first organ system! – The integumentary system Wednesday: Review day! – Chapters 1-5 Friday: First exam! – Yay!